Clinical data | |
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Other names | Δ8-14-Isoestrone; 8-Dehydro-14-isoestrone; 14-Isoestra-1,3,5(10),8-tetraen-3-ol-17-one |
Routes of administration | By mouth |
Drug class | Estrogen |
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Chemical and physical data | |
Formula | C18H20O2 |
Molar mass | 268.356 g·mol−1 |
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Hippulin, also known as Δ8-14-isoestrone, as well as 14-isoestra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses and an isomer of equilin.[1][2][3][4] The compound, likely in sodium sulfate form, is a component of conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares,[1][2][3] though it is present only in small amounts in pregnant mare urine.[5] It has been reported by possess either equivalent estrogenic activity to that of equilin or only slight estrogenic activity.[3] The compound was first described in 1932.[4][3]
ERTooltip Estrogen receptor |
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GPERTooltip G protein-coupled estrogen receptor |
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