This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article provides insufficient context for those unfamiliar with the subject. Please help improve the article by providing more context for the reader. (April 2014) (Learn how and when to remove this message) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: "Timepidium bromide" – news · newspapers · books · scholar · JSTOR (July 2021) (Learn how and when to remove this message) (Learn how and when to remove this message)
Timepidium bromide
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		SC, IM, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H22BrNOS2
Molar mass400.39 g·mol−1
3D model (JSmol)
  • C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-]
  • InChI=1S/C17H22NOS2.BrH/c1-18(2)11-13(10-14(12-18)19-3)17(15-6-4-8-20-15)16-7-5-9-21-16;/h4-9,14H,10-12H2,1-3H3;1H/q+1;/p-1 ☒N
  • Key:QTSXMEPZSHLZFF-UHFFFAOYSA-M ☒N
 ☒NcheckY (what is this?)  (verify)

Timepidium bromide (INN) is an anticholinergic. It is used in the symptomatic treatment of visceral spasms.[1] It is also used to relieve pain associated with various gastrointestinal disorders.[2] The quaternary nitrogen prevents it from crossing the blood brain barrier, so it is peripherally acting with no central side effects.

The same compound sans the quaternary methyl group and the methoxy ether is called tipepidine.[3]

References

  1. ^ "Timepidium bromide: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia". www.mims.com. Retrieved 2021-07-05.
  2. ^ "Timepidium Bromide Tablets 30mg SAWAI 100 Tablets｜Natural Pharmacy". www.mimaki-family-japan.com. Retrieved 2021-07-05.
  3. ^ Shah R, Verma PK (December 2018). "Therapeutic importance of synthetic thiophene". Chemistry Central Journal. 12 (1): 137. doi:10.1186/s13065-018-0511-5. PMC 6768136. PMID 30564984.


Categories