mir-370 | |
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Identifiers | |
Symbol | mir-370 |
Rfam | RF00740 |
miRBase family | MIPF0000167 |
Other data | |
RNA type | microRNA |
Domain(s) | Eukaryota; |
PDB structures | PDBe |
In molecular biology mir-370 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. This microRNA, mir-370-3p, has been shown to play a role in heart failure. The upregulation of mir-370-3p in the sinus node leads to downregulation of the pacemaker ion channel, HCN4, and thus downregulation of the corresponding ionic current, which causes sinus bradycardia.[1]
miRNA precursor families | |
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1-100 | |
101-200 | |
201-300 | |
301-400 | |
401+ | |
Other |