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((short description|none))

((IARC groups))
'''IARC group 3''' substances, [[chemical mixture]]s and exposure circumstances are those that can not be classified in regard to their carcinogenicity to humans by the [[International Agency for Research on Cancer]] (IARC). This category is used most commonly for agents, mixtures and exposure circumstances for which the [[level of evidence]] of carcinogenicity is inadequate in humans and inadequate or limited in [[experimental animal]]s. Exceptionally, agents (mixtures) for which the evidence of carcinogenicity is inadequate in humans, but sufficient in experimental animals may be placed in this category when there is strong evidence that the mechanism of carcinogenicity in experimental animals does not operate in humans. Agents, mixtures and exposure circumstances that do not fall into any other group are also placed in this category.

This list is focusing on the [[hazard]] linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their [[risk]] into account, which is the probability of causing a cancer given the level of exposure to this carcinogenic agent.<ref>((cite web|title=IARC monographs preamble (as amended in 2019)|url=https://monographs.iarc.who.int/wp-content/uploads/2019/07/Preamble-2019.pdf|publisher=International Agency for Research on Cancer |accessdate=August 18, 2023|quote=A cancer hazard is an agent that is capable of causing cancer, whereas a cancer risk is an estimate of the probability that cancer will occur given some level of exposure to a cancer hazard.))</ref> The list is uptodate as of January 2024.<ref>((Cite web |title=List of Classifications – IARC Monographs on the Identification of Carcinogenic Hazards to Humans |url=https://monographs.iarc.who.int/list-of-classifications |access-date=2024-02-01 |website=monographs.iarc.who.int))</ref>

==Agents and groups of agents==

===A===
((div col|colwidth=30em))
*[[Acenaphthene]]
*[[Acepyrene]]
*[[Aciclovir]]
*[[Acridine orange]]
*[[Acriflavinium chloride]]
*[[Acrylic acid]]
*[[Acrylic fibre]]s
*[[Acrylonitrile-butadiene-styrene]] copolymers
*[[Actinomycin]] D
*[[Agaritine]]
*[[Aldicarb]]
*[[Aldrin]]
*[[Allyl chloride]]
*[[Allyl isothiocyanate]]
*[[Allyl isovalerate]]
*[[Amaranth (dye)]]
*[[5-Aminoacenaphthene]]
*[[2-Aminoanthraquinone]]
*[[para-Aminobenzoic acid]]
*[[1-Amino-2-methylanthraquinone]]
*[[2-Amino-4-nitrophenol]]
*[[2-Amino-5-nitrophenol]]
*[[4-Amino-2-nitrophenol]]
*[[2-Amino-5-nitrothiazole]]
*[[11-Aminoundecanoic acid]]
*[[Amitrole]]
*[[Ampicillin]]
*[[Anaesthetic]]s, volatile
*[[Angelicin]] plus ultraviolet A radiation
*[[para-Anisidine]]
*[[Anthanthrene]]
*[[Anthracene]]
*[[Anthranilic acid]]
*[[Antimony trisulfide]]
*[[Apholate]]
*para-[[Aramid]] fibrils
*[[Atrazine]]
*[[Aurothioglucose]] ([[Auranofin]])
*[[2-(1-Aziridinyl)ethanol]]
*[[Aziridyl benzoquinone]]
*[[Azobenzene]]
((div col end))

===B===
((div col|colwidth=30em))
*11''H''-Benz[''bc'']aceanthrylene
*Benz[''l'']aceanthrylene
*Benz[''a'']acridine
*Benz[''c'']acridine
*Benzo[''g'']chrysene
*Benzo[''a'']fluoranthene
*Benzo[''ghi'']fluoranthene
*Benzo[''a'']fluorene
*Benzo[''b'']fluorene
*Benzo[''c'']fluorene
*Benzo[''ghi'']perylene
*[[Benzo(e)pyrene|Benzo[''e'']pyrene]]
*''p''-Benzoquinone dioxime
*[[Benzoyl peroxide]]
*[[Benzyl acetate]]
*[[Bis(1-aziridinyl)morpholinophosphine sulfide]]
*[[Bis(2-chloroethyl)ether]]
*[[1,2-Bis(chloromethoxy)ethane]]
*[[1,4-Bis(chloromethoxymethyl)benzene]]
*[[Bis(2-chloro-1-methylethyl)ether]]
*[[Bis(2,3-epoxycyclopentyl)ether]]
*[[Bisphenol A diglycidyl ether]] (Aralditeâ)
*[[Bisulfite]]s
*[[Blue VRS]]
*[[Brilliant Blue FCF]], disodium salt
*[[Bromochloroacetonitrile]]
*[[Bromoethane]]
*[[Bromoform]]
*[[2-Butoxyethanol]]
*[[1-tert-Butoxy-2-propanol]]
*''n''-[[Butyl acrylate]]
*[[Butylated hydroxytoluene]] (BHT)
*[[Butyl benzyl phthalate]]
*''gamma''-[[Butyrolactone]]
((div col end))

===C===
((div col|colwidth=30em))
*[[Caffeine]]
*[[Cantharidin]]
*[[Caprolactam]]
*[[Captan]]
*[[Carbaryl]]
*[[3-Carbethoxypsoralen]]
*[[Carmoisine]]
*[[Carrageenan]]
*[[Chloramine]]
*[[Chlordimeform]]
*Chlorinated drinking water
*[[Chloroacetonitrile]]
*[[Chlorobenzilate]]
*[[Chlorodibromomethane]]
*[[Chlorodifluoromethane]]
*[[Chloroethane]]
*[[Chlorofluoromethane]]
*[[4-Chloro-meta-phenylenediamine]]
*[[Chloronitrobenzene]]s
*[[Chloropropham]]
*[[Chloroquine]]
*[[5-Chloro-ortho-toluidine]]
*[[2-Chloro-1,1,1-trifluoroethane]]
*[[Cholesterol]]
*[[Chromium]](III) compounds
*[[Chromium]], metallic
*[[Chrysoidine]]
*[[CI Acid Orange 3]]
*[[Cimetidine]]
*[[Cinnamyl anthranilate]]
*[[CI Pigment Red 3]]
*[[Citrinin]]
*[[Clofibrate]]
*[[Clomiphene citrate]]
*[[Coal dust]]
*[[Cobalt(II) sulfide]]
*[[Cobalt(II,III) oxide]]
**Other cobalt(II) compounds (not including soluble cobalt(II) salts, cobalt(II) oxide, cobalt(II,III) oxide, and cobalt(II) sulfde)
*[[Continuous glass filament]]
*[[Copper 8-hydroxyquinoline]]
*[[Coronene]]
*[[Coumarin]]
*''m''-[[Cresidine]]
*[[Cyclamate]]s
*[[Cyclochlorotine]]
*[[Cyclohexanone]]
*4''H''-Cyclopenta[''def'']chrysene
*[[5,6-Cyclopenteno-1,2-benzanthracene]]
((div col end))

===D===
((div col|colwidth=30em))
*[[D & C Red No. 9]]
*[[Dapsone]]
*[[Decabromodiphenyl oxide]]
*[[Deltamethrin]]
*[[Diacetylaminoazotoluene]]
*[[Diallate]]
*[[1,2-Diamino-4-nitrobenzene]]
*[[1,4-Diamino-2-nitrobenzene]]
*[[2,5-Diaminotoluene]]
*[[Diazepam]]
*[[Diazomethane]]
*Dibenz[''a,c'']anthracene
*[[Dibenz(a,j)anthracene|Dibenz[''a,j'']anthracene]]
*Dibenzo-''p''-dioxin
*Dibenzo[''a,e'']fluoranthene
*13''H''-Dibenzo[''a,g'']fluorene
*Dibenzo[''h,rst'']pentaphene
*Dibenzo[''a,e'']pyrene
*Dibenzo[''e,l'']pyrene
*[[Dichloroacetonitrile]]
*[[Dichloroacetylene]]
*''m''-[[Dichlorobenzene]]
*''o''-[[Dichlorobenzene]]
*''trans''-1,4-Dichlorobutene
*2,6-Dichloro-''p''-phenylenediamine
*[[Dicofol]]
*[[Didanosine]]
*[[Di(2-ethylhexyl) adipate]]
*[[Di(2-ethylhexyl) phthalate]]
*[[N,N'-Diethylthiourea]]
*[[1,2-Dihydroaceanthrylene]]
*[[Dihydroxymethylfuratrizine]]
*[[Dimethoxane]]
*[[3,3'-Dimethoxybenzidine-4,4'-diisocyanate]]
*''p''-Dimethylaminoazobenzenediazo sodium sulfonate
*[[4,4'-Dimethylangelicin]] plus ultraviolet A radiation
*[[4,5'-Dimethylangelicin]] plus ultraviolet A radiation
*[[N,N-Dimethylaniline]]
*[[1,4-Dimethylphenanthrene]]
*[[3,5-Dinitrotoluene]]
*[[Dinitrosopentamethylenetetramine]]
*[[2,4'-Diphenyldiamine]]
*[[Disperse Yellow 3]]
*[[Disulfiram]]
*[[Dithranol]]
*[[Doxefazepam]]
*[[Doxylamine succinate]]
*[[Droloxifene]]
*[[Dulcin]]
((div col end))

===E&ndash;G===
((div col|colwidth=30em))
*[[Electric field]]s (extremely low-frequency)
*[[Electric field]]s (static)
*[[Endrin]]
*[[Eosin]]
*[[3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6-methylcyclo-hexanecarboxylate]]
*[[cis-9,10-Epoxystearic acid]]
*[[Estazolam]]
*[[Ethionamide]]
*[[Ethylene]]
*[[Ethylene sulfide]]
*[[Ethylenethiourea]]
*[[Ethyl selenac]]
*[[Ethyl tellurac]]
*[[Eugenol]]
*[[Evans blue (dye)|Evans blue]]
*[[Fast Green FCF]]
*[[Fenvalerate]]
*[[Ferbam]]
*[[Iron(III) oxide|Ferric oxide]]
*[[Fluometuron]]
*[[Fluoranthene]]
*[[Fluorene]]
*[[Fluorescent lighting]]
*[[Fluoride]]s (inorganic, used in drinking-water)
*[[5-Fluorouracil]]
*Foreign bodies, implanted in tissues
**Metallic [[chromium]] or [[titanium]], [[cobalt]]-based, [[chromium]]-based and [[titanium]]-based [[alloy]]s, [[stainless steel]] and [[depleted uranium]]
*[[Furazolidone]]
*[[Furfural]]
*[[Furosemide]] (Frusemide)
*[[Gemfibrozil]]
*[[Glycidyl oleate]]
*[[Glycidyl stearate]]
*[[Guinea Green B]]
*[[Gyromitrin]]
((div col end))

===H&ndash;L===
((div col|colwidth=30em))
*[[Haematite]]
*[[HC Blue No. 2]]
*[[HC Red No. 3]]
*[[HC Yellow No. 4]]
*[[Hepatitis D virus]]
*[[Hexachlorobutadiene]]
*[[Hexachlorophene]]
*Human T-cell lymphotropic virus type II
*[[Hycanthone mesylate]]
*[[Hydralazine]]
*[[Hydrochloric acid]]
*[[Hydrogen peroxide]]
*[[Hydroquinone]]
*[[4-Hydroxyazobenzene]]
*[[8-Hydroxyquinoline]]
*[[Hydroxysenkirkine]]
*[[Hydroxyurea]]
*[[Hypochlorite]] salts
*Insulation [[glass wool]]
*Iron-dextrin complex
*Iron sorbitol-citric acid complex
*[[Isatidine]]
*Isonicotinic acid hydrazide ([[Isoniazid]])
*[[Isophosphamide]]
*[[Isopropanol]]
*Isopropyl oils
*[[Isosafrole]]
*[[Jacobine]]
*[[Kaempferol]]
*[[Kojic acid]]
*[[Lauroyl peroxide]]
*[[Lead]] compounds, organic
*Leucogentian violet
*[[Light Green SF]]
*''D''-[[Limonene]]
*[[Luteoskyrin]]
((div col end))

===M===
((div col|colwidth=30em))
*Madder root (''[[Rubia tinctorum]]'')
*[[Magnetic field]]s (static)
*[[Malachite green]]
*[[Maleic hydrazide]]
*[[Malonaldehyde]]
*[[Maneb]]
*[[Mannomustine dihydrochloride]]
*[[Medphalan]]
*[[6-Mercaptopurine]]
*[[Mercury (element)|Mercury]] and inorganic mercury compounds
*[[Metabisulfite]]s
*[[Methimazole]]
*[[Methotrexate]]
*[[Methoxychlor]]
*[[5-Methylangelicin]]
*[[Bromomethane|Methyl bromide]]
*[[Methyl tert-butyl ether]]
*[[Methyl carbamate]]
*[[Chloromethane|Methyl chloride]]
*[[1-Methylchrysene]]
*[[2-Methylchrysene]]
*[[3-Methylchrysene]]
*[[4-Methylchrysene]]
*[[6-Methylchrysene]]
*[[N-Methyl-N,4-dinitrosoaniline]]
*[[4,4'-Methylene bis(N,N-dimethyl)benzenamine]]
*[[4,4'-Methylenediphenyl diisocyanate]]
*[[2-Methylfluoranthene]]
*[[3-Methylfluoranthene]]
*[[Methylglyoxal]]
*[[Iodomethane|Methyl iodide]]
*[[Methyl methacrylate]]
*[[Methyl parathion]]
*[[1-Methylphenanthrene]]
*7-Methylpyrido[3,4-''c'']psoralen
*[[Methyl red]]
*[[Methyl selenac]]
*''Microcystis'' extracts
*[[Modacrylic fibre]]s
*[[Monuron]]
*[[Morpholine]]
*[[Musk ambrette]]
*[[Musk xylene]]
((div col end))

===N&ndash;O===
((div col|colwidth=30em))
*[[1,5-Naphthalenediamine]]
*[[1,5-Naphthalene diisocyanate]]
*Naphtho[1,2-''b'']fluoranthene
*Naphtho[2,1-''a'']fluoranthene
*Naphtho[2,3-''e'']pyrene
*[[1-Naphthylamine]]
*[[1-Naphthylthiourea]] (ANTU)
*[[Nithiazide]]
*[[5-Nitro-ortho-anisidine]]
*[[9-Nitroanthracene]]
*7-Nitrobenz[''a'']anthracene
*6-Nitrobenzo[''a'']pyrene
*[[4-Nitrobiphenyl]]
*[[3-Nitrofluoranthene]]
*[[Nitrofural]] (Nitrofurazone)
*[[Nitrofurantoin]]
*[[1-Nitronaphthalene]]
*[[2-Nitronaphthalene]]
*[[3-Nitroperylene]]
*[[2-Nitropyrene]]
*[[N'-Nitrosoanabasine]]
*[[N'-Nitrosoanatabine]]
*[[N-Nitrosodiphenylamine]]
*[[para-Nitrosodiphenylamine]]
*[[N-Nitrosofolic acid]]
*[[N-Nitrosoguvacine]]
*[[N-Nitrosoguvacoline]]
*[[N-Nitrosohydroxyproline]]
*[[3-(N-Nitrosomethylamino)propionaldehyde]]
*[[4-(N-Nitrosomethylamino)-4-(3-pyridyl)-1-butanal]] (NNA)
*[[N-Nitrosoproline]]
*[[Nitrotoluene]]s
*[[5-Nitro-ortho-toluidine]]
*[[Nitrovin]]
*[[Nodularin]]s
*[[Nylon]] 6
*[[Oestradiol mustard]]
*''[[Opisthorchis felineus]]'' (infection with)
*[[Orange I]]
*[[Orange G]]
*[[Oxyphenbutazone]]
((div col end))

===P===
((div col|colwidth=30em))
*[[Palygorskite]] (attapulgite) (short fibres, < 5 micrometers)
*[[Paracetamol]] (Acetaminophen)
*[[Parasorbic acid]]
*[[Patulin]]
*[[Penicillic acid]]
*[[Pentachloroethane]]
*[[Pentavalent antimonial|Pentavalent antimony]]
*[[Permethrin]]
*[[Perylene]]
*[[Petasitenine]]
*[[Phenanthrene]]
*[[Phenelzine sulfate]]
*[[Phenicarbazide]]
*[[Phenol]]
*[[Phenylbutazone]]
*[[meta-Phenylenediamine]]
*[[para-Phenylenediamine]]
*[[N-Phenyl-2-naphthylamine]]
*[[ortho-Phenylphenol]]
*[[Picene]]
*[[Picloram]]
*[[3-Methylpyridine|β-Picoline]]
*[[Piperonyl butoxide]]
*[[Polyacrylic acid]]
*Polychlorinated dibenzo-''p''-[[Polychlorinated dibenzodioxins|dioxins]] (other than 2,3,7,8-tetrachlorodibenzo-''p''-dioxin)
*Polychlorinated dibenzofurans
*[[Polychloroprene]]
*[[Polyethylene]]
*Polymethylene polyphenyl isocyanate
*[[Perspex|Polymethyl methacrylate]]
*[[Polypropylene]]
*[[Polystyrene]]
*[[PTFE|Polytetrafluoroethylene]] (Teflon)
*[[Polyurethane]] foams
*[[Polyvinyl acetate]]
*[[Polyvinyl alcohol]]
*[[Polyvinyl chloride]]
*[[Polyvinyl pyrrolidone]]
*[[Ponceau SX]]
*[[Potassium bis(2-hydroxyethyl)dithiocarbamate]]
*[[Prazepam]]
*[[Prednimustine]]
*[[Prednisone]]
*[[Proflavine]] salts
*[[Pronetalol]] hydrochloride
*[[Propham]]
*''n''-[[Propyl carbamate]]
*[[Propylene]]
*[[Ptaquiloside]]
*[[Pyrene]]
*[[Pyridine]]
*Pyrido[3,4-''c'']psoralen
*[[Pyrimethamine]]
((div col end))

===Q&ndash;R===
((div col|colwidth=30em))
*[[Quercetin]]
*[[para-Quinone]]
*[[Quintozene]] ([[Pentachloronitrobenzene]])
*[[Reserpine]]
*[[Resorcinol]]
*[[Retrorsine]]
*[[Rhodamine B]]
*[[Rhodamine 6G]]
*[[Rifampicin]]
*[[Ripazepam]]
*[[Rock wool|Rock (stone) wool]]
*[[Rugulosin]]
((div col end))

===S===
((div col|colwidth=30em))
*Saccharated iron oxide
*[[Saccharin]] and its salts
*[[Scarlet Red]]
*''[[Schistosoma mansoni]]'' (infection with)
*[[Selenium]] and selenium compounds
*[[Semicarbazide]] hydrochloride
*[[Seneciphylline]]
*[[Senkirkine]]
*[[Sepiolite]]
*[[Shikimic acid]]
*[[Silica]], amorphous
*[[Simazine]]
*Slag wool
*[[Sodium chlorite]]
*[[Sodium diethyldithiocarbamate]]
*[[Spironolactone]]
*Styrene-acrylonitrile copolymers
*Styrene-butadiene copolymers
*[[Succinic anhydride]]
*[[Sudan I]]
*[[Sudan II]]
*[[Sudan III]]
*[[Sudan Brown RR]]
*[[Sudan Red 7B]]
*[[Sulfafurazole]] (Sulfisoxazole)
*[[Sulfamethazine]]
*[[Sulfamethoxazole]]
*[[Sulfite]]s
*[[Sulfur dioxide]]
*[[Sunset Yellow FCF]]
*[[Surgical implant]]s
**Orthopaedic implants and devices, of complex composition
**[[Cardiac pacemaker]]s
**Dental materials
**[[Ceramic]] materials
*[[Surgical implant]]s, [[Breast implant|female breast reconstruction]], [[silicone]]
*[[Symphytine]]
((div col end))

===T===
((div col|colwidth=30em))
*[[Talc]], not containing asbestiform fibres
*[[Tannic acid]] and [[tannin]]s
*[[Temazepam]]
*[[2,2',5,5'-Tetrachlorobenzidine]]
*Tetrakis(hydroxymethyl)phosphonium salts
*[[Theobromine]]
*[[Theophylline]]
*[[Thiourea]]
*[[Thiram]]
*[[Toluene]]
*[[Toremifene]]
*[[Toxin]]s derived from ''[[Fusarium graminearum]]'', ''[[Fusarium culmorum|F. culmorum]]'' and ''[[Fusarium crookwellense|F. crookwellense]]'' ([[zearalenone]], [[deoxynivalenol]], [[nivalenol]], and [[fusarenone X]])
*[[Toxin]]s derived from ''[[Fusarium sporotrichioides]]''
*[[Trichlorfon]]
*[[Trichloroacetonitrile]]
*[[1,1,2-Trichloroethane]]
*[[Triethanolamine]]
*[[Triethylene glycol diglycidyl ether]]
*[[Trifluralin]]
*[[4,4',6-Trimethylangelicin]] plus ultraviolet A radiation
*[[2,4,5-Trimethylaniline]]
*[[2,4,6-Trimethylaniline]]
*[[4,5',8-Trimethylpsoralen]]
*[[2,4,6-Trinitrotoluene]]
*[[Triphenylene]]
*[[Tris(aziridinyl)-para-benzoquinone]] ([[Triaziquone]])
*[[Tris(1-aziridinyl)phosphine oxide]]
*[[2,4,6-Tris(1-aziridinyl)-s-triazine]]
*[[Tris(2-chloroethyl) phosphate]]
*[[1,2,3-Tris(chloromethoxy)propane]]
*[[Tris(2-methyl-1-aziridinyl)phosphine oxide]]
((div col end))

===U&ndash;Z===
((div col|colwidth=30em))
*[[Vat Yellow 4]]
*[[Vinblastine sulfate]]
*[[Vincristine sulfate]]
*Vinyl chloride-vinyl acetate copolymers
*Vinylidene chloride-vinyl chloride copolymers
*[[Vinylidene fluoride]]
*[[N-Vinylpyrrolidone|N-Vinyl-2-pyrrolidone]]
*[[Vinyl toluene]]
*[[Vitamin K]] substances
*[[Wollastonite]]
*[[Xylene]]s
*[[2,4-Xylidine]]
*[[2,5-Xylidine]]
*Yellow AB
*Yellow OB
*[[Zectran]]
*[[Zeolite]]s other than [[erionite]] ([[clinoptilolite]], [[phillipsite]], [[mordenite]], non-fibrous Japanese zeolite, synthetic zeolites)
*[[Zineb]]
*[[Ziram]]
((div col end))

==Mixtures==
((div col|colwidth=30em))
* [[Bitumen]]s, steam-refined, cracking-residue and air-refined
* [[Coffee]], drinking
* [[Crude oil]]
* [[Diesel fuel]]s, distillate (light)
* [[Fuel oil]]s, distillate (light)
* [[Jet fuel]]
* [[Mate (beverage)|Mate]], not very hot (drinking)
* [[Mineral oil]]s, highly refined
* Petroleum solvents
* Printing [[ink]]s
* [[Tea]]
* [[Terpene]] polychlorinates ([[Strobane]]®)
((div col end))

==Exposure circumstances==
((div col|colwidth=30em))
*[[Calcium carbide]] production
* Flat-glass and specialty glass (manufacture of)
* Hair colouring products (personal use of)
* Leather goods manufacture
* Leather tanning and processing
* Lumber and sawmill industries (including logging)
* Paint manufacture (occupational exposure in)
* Pulp and paper manufacture
((div col end))

==See also==
* [[IARC group 1]]
* [[IARC group 2A]]
* [[IARC group 2B]]

== References ==
((Reflist))

((portal|Lists|Medicine))
((more citations needed|date=August 2023))

==External links==
* [http://monographs.iarc.fr/ENG/Classification/ Description of the list of classifications], [[International Agency for Research on Cancer|IARC]]
** [https://monographs.iarc.fr/list-of-classifications List of Classifications] (latest version)
<!-- ** [http://monographs.iarc.fr/ENG/Classification/ClassificationsGroupOrder.pdf Agents Classified], (last updated on 7 April 2015) (((old version of the same thing from the previous link, so hide it))) -->
** [http://monographs.iarc.fr/ENG/Classification/Table4.pdf List of classifications by cancer site] ((Webarchive|url=https://web.archive.org/web/20120920150724/http://monographs.iarc.fr/ENG/Classification/Table4.pdf |date=2012-09-20 )) (last updated on 5 November 2015)

((Carcinogen))

((DEFAULTSORT:IARC Group 3 possible carcinogens))
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[[Category:Suspected carcinogens]]
[[Category:Science-related lists]]

[[ja:IARC発がん性リスク一覧]]

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