Substitution may refer to:

• Substitution reaction

• Substitution cipher, a method of encryption
• Integration by substitution, a method for finding antiderivatives and integrals

• Substitution (sport), where a sports team is able to change one player for another during a match

• Help:Substitution, help performing substitution on Wikipedia pages
• Special:ExpandTemplates, page that shows what will result from substitution
• Wikipedia:Substitution, where, when, how, and what about using substitution on Wikipedia

• Substituent, an atom or group of atoms

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