5-hydroxytryptophanum est serotonini antecessor chemicus.

5-hydroxytryptophanum sive oxitriptanum (INN) est acidum aminicum naturale atque antecessor chemicus apud neurotransmissoris synthesin serotonini.

Natura chemica

Massa molaris est 220.23 g/mol.

Natura biochemica

Sub vim enzymi L-Aminoacidorum aromaticorum decarboxylasis (AADC) 5-hydroxytryptophanum decarboxylationem passo in 5-hydroxytryptaminum (serotoninum) mutatur. Pro hae reactione vitaminum B6 necesse est [1].

Usus

In variis civitatibus 5-hydroxytryptophanum remedium depressionis et insomnia et inappetentia offertur (supplementum alimentarium).

Notae

  1. ↑ Rahman MK, Nagatsu T, Sakurai T, Hori S, Abe M, Matsuda M (1982). Effect pf pyridoxal phosphate deficiency on aromatic L-amino acid decarboxylaxse activity with L-DOPA and L-5-hydroxytryptophan as substrates in rats journal=Jap J Pharmacology. 32. pp. 803-11 

Nexus interni

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