Zephyrinus is a Latin masculine name (derived from the Greek Ζεφυρος, the name of the west wind). The name has related forms in modern languages:

• Zéphyrin or Zéphirin (French); feminine: Zéphyrine
• Zephyrin or Zephirin (German); feminine Zephryine
• Zeferino (Italian); feminine: Zeferina
• Ceferino, Zeferino or Seferino (Spanish); feminine: Ceferina, Zeferina or Seferina

The name can refer to the following:

People

Men

• Pope Zephyrinus (died 217), pope and saint
• Zepherinus Joseph (born 1975), Saint Lucia athlete
• Zéphyrin or Zepherin Ferrez (1797–1851), French-Brazilian sculptor and engraver
• Zéphirin Diabré (born 1959), Burkina Faso politician
• Zéphirin Gerbe (1810–1890), French naturalist
• Zephyrin Engelhardt (1851–1934), German Franciscan and historian
• Zéphyrin Camélinat(1840–1932), French communist and political activist
• Zéphyrin Toé (1928–2013), Burkina Faso bishop
• Louis-Zéphirin Joncas (1846–1903), Canadian journalist and politician
• Louis-Zéphirin Moreau (1824–1901), German bishop

Women

• Marie Zéphyrine of France (1750–1755), French princess
• Princess Amalie Zephyrine of Salm-Kyrburg (1760–1841), German princess