ydaO/yuaA leader | |
---|---|
![]() Predicted secondary structure and sequence conservation of ydaO-yuaA | |
Identifiers | |
Symbol | ydaO-yuaA |
Rfam | RF00379 |
Other data | |
RNA type | Cis-reg; riboswitch |
Domain(s) | Bacteria |
SO | SO:0000233 |
PDB structures | PDBe |
The YdaO/YuaA leader (now called the cyclic di-AMP riboswitch) is a conserved RNA structure found upstream of the ydaO and yuaA genes in Bacillus subtilis and related genes in other bacteria. Its secondary structure and gene associations were predicted by bioinformatics.[1]
These RNAs function as riboswitches, and sense the signaling molecule cyclic di-AMP.[2] The interaction between the riboswitch and c-di-AMP has been revealed in atomic-resolution structures.[3][4][5]