The Three Amigos was a series of public service announcements to promote safe sexual practices that could be helpful in preventing the transmission of HIV/AIDS. It consisted of 20 episodes with three animated characters in the shape of condoms.^[1]

The series was first screened at the XV International AIDS Conference in 2004 and received a global launch in 2005 and was subsequently translated into six different languages. This series was reached to audience through broadcast as well as distribution by non-governmental organizations, educational institutions, hospitals, and various groups across 150 countries and in 45 languages in 2012.

The series was a collaborative effort of both Firdaus Kharas and Brent Quinn. All the episodes had humorous content with time duration of 15-60 seconds. The campaign relied extensively on hand-drawn animation, created by volunteers from four different countries. Its distribution was conducted free of charge.

The campaign won a Peabody Award in 2006, among 29 other international accolades. Since its release, the series has been the subject of numerous articles and academic discussions. Supporters of the campaign included notable figures such as Nobel Peace Prize winner laureate Archbishop Desmond Tutu, who expressed public support for the initiative.