Creating a redirect for this article[edit]

I suggest that this article should redirect to the systematic name for norleucine since the International Union of Biochemistry rules for naming discourage the use of norleucine and suggest the systematic name is most appropriate. Additionally, the main reason they suggest this is that norleucine is actually a misnomer, given that nor is defined as an amino acid with one less methylene group than standard, which is not the case with this compound. I am not familiar with all of the nuances of wikipedia editing. I generally correct things I stumble across that I know to be wrong so I don't know how to create a redirect without manually editing every link to the article. Hopefully someone can come along and effect this change. — Preceding unsigned comment added by 46.126.91.225 (talkcontribs) 13:50, 28 June 2014‎ (UTC)[reply]

Requested move (July 2014)[edit]

The following discussion is an archived discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. Editors desiring to contest the closing decision should consider a move review. No further edits should be made to this section.

The result of the move request was: not moved. Jenks24 (talk) 11:50, 8 August 2014 (UTC)[reply]



Norleucine(2S)-2-aminohexanoic acid – Please refer to the following reference: Nomenclature and Symbolism For Amino Acids and Peptides. Pure and Applied Chemistry, Vol. 56, No. 5, pp.595-624, 1984. Norleucine, while a common name for this compound, is in fact a complete misnomer, as discussed in the article. The approved naming convention would be to use the systematic name as it is short. Thus, having norleucine redirect to the systematic name is the most appropriate choice here. Relisted. Jenks24 (talk) 11:47, 31 July 2014 (UTC) Relisted. Jenks24 (talk) 14:31, 24 July 2014 (UTC) 130.60.228.85 (talk) 10:50, 16 July 2014 (UTC)[reply]

Keep Norleucine. This is the name chemists and biochemists and biomedical people call this compound, whether we like it or not and if our intention is to help readers vs right great wrongs, we should stick with the ordinary usage. This morning I searched a Chemical Abstracts Service (recorder of all publications in bio- and chemical sciences) gave these results: 6291 references to norleucine and 122 references to 2-aminohexanoic acid. I understand the frustration that some editors have with a lot of weird names and their good intentions of fixing things, but this is another case where the name change would not serve readers, in my opinion. --Smokefoot (talk) 12:34, 31 July 2014 (UTC)[reply]
Keep Norleucine. That is what people prefer to call it. (And in my opinion they do so with good reason. But that's irrelevant to this discussion.) Maproom (talk) 13:45, 31 July 2014 (UTC)[reply]

The above discussion is preserved as an archive of a requested move. Please do not modify it. Subsequent comments should be made in a new section on this talk page or in a move review. No further edits should be made to this section.

Chemical Abstracts search for 2013-2014[edit]

Below are the first four hits for a search for "norleucine" in Chemical Abstracts for the years 2013-. 194 hits with that term. Prior to 2013, another 5,200 citations to this term in the scientific literature.

Quick View Full Text By Goursaud, Stephanie; Schafer, Sabrina; Dumont, Amelie O.; Vergouts, Maxime; Gallo, Alessandro; Desmet, Nathalie; Deumens, Ronald; Hermans, Emmanuel From Experimental Neurology (2014), Ahead of Print.  |  Language: English, Database: CAPLUS

Quick View Full Text By Torres, M. Edite; dos Santos, A. P. Marreilha; Goncalves, Luisa L.; Andrade, Vanda; Batoreu, M. Camila; Mateus, M. Luisa From Environmental Toxicology and Pharmacology (2014), 38(3), 807-813.  |  Language: English, Database: CAPLUS The interference of N-acetylcysteine (NAC) on 2,5-hexanedione (2,5-HD) neurotoxicity was evaluated through behavioral assays and the anal. of urinary 2,5-HD, dimethylpyrrole norleucine (DMPN), and cysteine-pyrrole conjugate (DMPN NAC), by ESI-LC-MS/MS, in rats exposed to 2,5-HD and co-exposed to 2,5-HD and

Quick View Full Text By Freeman, Kevin From PCT Int. Appl. (2014), WO 2014160071 A1 20141002.  |  Language: English, Database: CAPLUS Provided herein are methods for a novel combination therapy for treating a glutamine-addicted cancer in a subject in need thereof, which comprises the administration of a glutaminase antagonist and a pro-apoptotic compd.  Specific glutaminase antagonists and pro-apoptotic compds. are provided.  In some embodiments, the glutaminase antagonist is 6-diazo-5-oxo-1-norleucine (DON) and the pro-apoptotic compd. is a Bcl-2 family member antagonist.  In some

Quick View Full Text By Geetha, P.; Arulmozhi, S.; Madhavan, J.; Raj, M. Victor Antony From International Journal of ChemTech Research (2014), 6(3S), 1647-1650, 4.  |  Language: English, Database: CAPLUS Org. materials are promising candidates since their properties can be custom-tailored, and their dielec. consts. and refractive indexes are much smaller than those of the most common inorg. materials.  A novel org. single crystal of L-isoleucine-D-norleucine was grown from solns. by slow evapn. technique.  Powder XRD Conclusion: norleucine is a commonly name and Wikipedia reflects this usage. --Smokefoot (talk) 14:34, 20 October 2014 (UTC)[reply]

PubMed search for Norleucine[edit]

I just searched for exact phrases for 2-aminohexanoic acid, 2-aminohexanoicacid and 2-aminohexanoate, and got a total of 24 hits. Norleucine, the common name, returns 1305 hits. Also, searching for just aminohexanoic returned hits, which at a short glance, do not appear to belong to 2-aminohexanoic acid at all, but different compounds. To me, this shows that Norleucine is the accepted and used name for this compound among medical scientists, biologists, and (more importantly) biochemists, which all use NCBI's PubMed as their primary citation database. Enozkan (talk) 23:27, 19 January 2015 (UTC)[reply]