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In August 2016 a Phase I phase 1, double-blind, parallel, randomized, placebo-controlled clinical trial was undertaken by the Danish Statens Serum Institut at Hammersmith Hospital in London, UK, in healthy women aged 19–45 years. The trial aimed to assess the safety and ability to provoke an immune response of the CTH522 chlamydia vaccine. 35 women not infected with chlamydia were included in the trial. The trial included two adjuvants and a saline control group. The vaccine was found to be safe, and all women who received the vaccine regardless of adjuvant developed an immune response against chlamydia. [1]
The Serum Institute has announced that it will continue to pursue funding to move the vaccine into a Phase II trial.[2]
betalactam refers to the ring srtucture, i believe the term you are looking for in treatment is BETA LACTAMASE. please fix this cos I don't know how to.
The page koala claims that koalas can have chlamydia. Aside from the obvious dirty jokes, some information about chlamydia in non-human species might be relevant here. --FOo 17:12, 24 Jan 2004 (UTC)It seems cougars or pumas are also having problems with this disease.
As far I’m concerned I think taxonomical names must be written in italic text, as the following: Escherichia coli or E. coli. Please, revise than question.
The Veronica Mars paragraph is irrelevant for this topic and should be removed. 15:52, 29 August 2006 (UTC)
Chlamydia is just as likely to occur when there is no recent sexual contact, recent onset of menses, or an IUD in place or if the partner has a sexually transmitted disease.
Is it possible to become infected with chlamydia without having sexual contact to an infected person? Can I take the quoted sentence from paragraph 3 of the article to mean that? --82.207.230.185 19:05, 14 February 2007 (UTC)
In the article, I read the following sentence:
Can someone replace the that sentence with a clearer explanation. The sentence tells me to consider several unpleasant conditions, or at least that someone must consider them. I wonder who must consider these conditions, when must they be considered, and why must these conditions be considered.
Moreover, it does not become clear whether the fact that these conditions must be considered has any relationship with the subject off this article, which is Chlamydia. I suppose it has, because someone wrote that sentence in this article and not in the article Influenza.
One more thing, could someone also explain how these conditions must be considered? Is it okay if I just lean back in my chair for five minutes, and quitly consider appendicitis and that other stuff? Or should something else be done as well? And I would welcome some links from those hard words to some applicable Wikipedia articles as well. Johan Lont 11:57, 13 March 2007 (UTC)
can you have sex with a partner thar has chalmydia and still not catch it if you were having sex with that person for 3 months straight unprotected, with out condoms,is that possible or was i cheated on? —Preceding unsigned comment added by 76.27.212.200 (talk) 22:19, 6 May 2009 (UTC)
I am not a native English speaker, but the sentence "It is can present similar to Neisseria gonorrhoeae "the clap" or in combination with it. sound like nonsense to me. Could someone rewrite it to clarify it? Nazgul02 (talk) 15:07, 8 January 2010 (UTC)
Can someone go into more detail about the "unusual discharge"? What is it? What is it made up of? Flashpoint145 02:06, 12 April 2007 (UTC)
Why does the page list a treatment (Ciprofloxacin) which comes under the heading 'untested' and a disclaimer saying it is shown to be ineffective? I don't see what this adds to the article apart from a disclaimer that breaks the layout due to not wrapping, unless this is a common treatment and listed to inform people of its lack of efficacy —The preceding unsigned comment was added by 82.152.221.253 (talk) 22:00, 27 April 2007 (UTC).
The images really did not identify anything, thus I have removed them. Before inserting them again, make sure to give a detailled descrption of what to look for on the images.
If you have a buring sensation while urinating dose it mean you deffinetly have a STD? Thank you in advance! Sorry about the spelling!
It would not necessarily be an STD. Burning during or after urination could indicate an STD, a urinary tract infection, or irritation of the urethra, BUT - If in doubt, get it checked out, untreated STDs can lead to fertility problems. BruceD270 16:42, 5 October 2007 (UTC)
Is it true that they put something in the eyes of babies when they are born to kill off this disease?
What is the procedure for determining if someone has Chlamydia? Is it a standard blood test?
Also, with regards to diagnosis to diagnosis of genitourinary infections (penis/vagina), guys can have a pee-in-the cup test, but women need what looks like a pap smear test. Makes sense since the urine doesn't come through the vagina, right? Adults RARELY get it in the eye. Babies get it there just b/c the mom is infected in her vagina (if she didn't get proper pre-natal care) and as the baby passes through the birth canal, it gets secretions in its eyes. Nowadays, no matter what, if a baby is born in a hospital, it's given erythromycin eye drops immediately. Unfortunately this is not always effective. Baby can also get pneumonia this way.Walking Softly 03:24, 20 October 2007 (UTC)
Chlamydia and oral sex It is given on [1] that Chlamydia is difficult to get by oral sex. The bacteria does not infect the oral area as much as the genitals.
The term "Reiter's syndrome" is absolutely still used. Sorry to hear about Reiter's association with Nazi's, but docs still use it and it's still taught in med schools and tested on the boards. The thing is, you can't apply it to simple reactive arthritis caused by chlamydia or gonorrhea. Reiter's syndrome refers to the triad (MUST have all 3 parts--you can't say patient has Reiter's syndrome minus conjunctivitis or some silliness like that) of reactive arthritis, conjunctivitis, and urethritis.
Can we take this bit out and instead explain what true Reiter's syndrome is or at least explain what reactive arthritis is?
Btw, reactive arthritis is something that could be avoided if the chlamydia/gonorrhea were treated immediately with antibiotics, but after the arthrtitis has established itself, it's really its own entitity, and must be treated like regular arthritis. Walking Softly 16:20, 20 October 2007 (UTC)
REMOVED BIT REGARDING HANS REITER (SEEMS UNNECESSARY, AND REALLY ISN'T TRUE): (Some forms of reactive arthritis formerly were known as Reiter's syndrome. The latter term has fallen out of favor owing to revelations about [[Hans Conrad Julius Reiter[]'s Nazi past and in particular his alleged active participation in horrific human experiments in concentration camps.)Walking Softly 14:24, 26 October 2007 (UTC)
Please look up facts and add citations where you can. There should be footnotes all over this page, and there are only TWO at present. Thank you:) Walking Softly 14:52, 26 October 2007 (UTC)
I think we need to combine this page with the existing one on 'Chlamydia trachomatis', and name the combined page, "Chlamydia trachomatis." When people type in plain ole "Chlamydia" or "Chlamydiae" into the search engine, it should come to "Chlamydia trachomatis," with options to redirect to all the other Chlamydia, and Chlamydophila pages. At present, I think it's just confusing. Thoughts?
A quick reworking of the intro:
Chlamydia (from the Greek, χλαμύδος meaning "cloak") is a common sexually transmitted disease (STD) caused by the bacterium, Chlamydia trachomatis. Chlamydia is a major infectious cause of human eye and genital disease.
C. trachomatis is naturally found living only inside human cells and is one of the most common sexually transmitted infections in people worldwide — about 2.8 million cases of chlamydia infection occur in the United States each year.[3] Chlamydia can be transmitted during vaginal, anal, or oral sex, and can be passed from an infected mother to her baby during vaginal childbirth. Many people with Chlamydia exhibit no symptoms of infection. Between half and three-quarters of all women who have chlamydia have no symptoms and do not know that they are infected. If untreated, chlamydial infections can cause serious reproductive and other health problems with both short-term and long-term consequences. Chlamydia is easily treated with antibiotics.
Of equal importance, chlamydia infection of the eye is the most common cause of preventable blindness in the world. Blindness occurs as a complication of trachoma (chlamydia conjunctivitis).[4]
References
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Hmm have just found the following, [2] which indicates that there are some clear issues with the taxonomy of some of these articles.--DO11.10 02:23, 27 October 2007 (UTC)
http://commons.wikimedia.org/wiki/Image:Pap_smear_showing_clamydia_in_the_vacuoles_500x_H%26E.jpg
I don't know what this is, but it's not chlamydia if it's H&E staining. Chlamydia in culture has to be stained with Geimsa stains or direct fluorescence antibody (see http://eyemicrobiology.upmc.com/Chlamydia.htm). If you disagree and want to say that H&E is possible, please reference a site. I really don't think it's possible. Geimsa can look like H&E, and I'm not the best with lab stuff, so I don't want to be the authority on this one, but I really think the picture and caption should at least be checked with an expert. Walking Softly 22:58, 27 October 2007 (UTC)
As an aside, I don't think it should be called a Pap smear. That traditionally refers to the sample and test for changes related to cervical cancer. Besides, at this level, I don't know that you can tell it's a Pap smear. Could be a sample from a guy's penis or a kid's eye. Cell culture would be a safer term and the only one I've ever heard used, though I'm not an Ob-gyn attending nor a Pathologist, so again, I don't want to come down hard on this one. Hey, maybe it IS a pap smear and stained with H&E, and I'm just too naive to know that that's somehow possible. Walking Softly 23:48, 27 October 2007 (UTC)
I disagree with the recent change stating that "Chlamydophila Infections" (e.g., Psittacosis) are also known as "Chlamydia", using MeSH as the reference. Please look closer at this link, and this one. (They could both be described as Chlamydiaceae infections, but I don't think such a page is needed at this time.) --Arcadian 00:38, 28 October 2007 (UTC)
The split of the genus into Chlamydia and Chlamydophila has been shown to be an erroneous inference based on a single gene, 16S rRNA. Subsequent complete genome sequencing showed that Chlamydophila and Chlamydia are not a monophyletic genera, and it is proposed that the original genus Chlamydia be restored.
"The previous taxonomic separation of the genus based on ribosomal sequences is neither consistent with the natural history of the organism revealed by genome comparisons, nor widely used by the Chlamydia research community 8 years after its introduction; thus, it is proposed to reunite the Chlamydiaceae into a single genus, Chlamydia."[1]
"Glossary. Chlamydiaceae: a family of obligate intracellular bacteria that once included two genera, Chlamydia and Chlamydophila, but has since been revised to the single genus Chlamydia"[2]
"We conclude that neither generally used 16S rRNA sequence identity cut-off values nor parameters based on genomic similarity consistently separate the two genera. Notably, no easily recognizable phenotype such as host preference or tissue tropism is available that would support a subdivision. In addition, the genus Chlamydophila is currently not well accepted and not used by a majority of research groups in the field. Therefore, we propose the classification of all currently recognized Chlamydiaceae species in a single genus, the genus Chlamydia."[3]
References
--Canavalia 00:36, 11 December 2018 (UTC)
This article was automatically assessed because at least one WikiProject had rated the article as start, and the rating on other projects was brought up to start class. BetacommandBot 16:25, 10 November 2007 (UTC)
((editsemiprotected)) Penultimate row of "Deaths per 100,000 table should read "100-110" instead of "100-90"
82.12.14.140 (talk) 22:09, 17 May 2010 (UTC)
((edit semi-protected)) Please change "(Although this is not an approved method of treatment.)" to "Due to the high risk of relapsing infection ciprofloxacin should not be used as a treatment of chlamydia infection." under Treatment, Untested treatments.
Please change "Untested treatments" to "Non-approved treatments"
Sources:
Fong IW, Linton W, Simbul M, Thorup R, McLaughlin B, Rahm V, Quinn PA. Treatment of nongonococcal urethritis with ciprofloxacin. Am J Med. 1987 Apr 27;82(4A):311-6. http://www.ncbi.nlm.nih.gov/pubmed/3555054
CIPROFLOXACIN IS INADEQUATE FOR CHLAMYDIAL URETHRITIS JWatch General 1990;1990:4-4. http://genmed.jwatch.org/cgi/content/full/1990/1002/4
Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro. Ute Dreses-Werringloer, Ingrid Padubrin, Barbara Jürgens-Saathoff, Alan P. Hudson, H. Zeidler and L. Köhler. Department of Rheumatology, Hannover Medical School, Hannover, Germany and Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, Michigan. 2000. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC90194/
124.157.108.202 (talk) 02:33, 16 September 2010 (UTC)
Add a section on prevention. Jidanni (talk) 02:12, 12 July 2012 (UTC)
Add the IPA pronunciation. Is it read "CLAM"-? Jidanni (talk) 02:12, 12 July 2012 (UTC)
Chlamydial infection is the most common bacterial sexually transmitted infection in the UK. [1]
References
"Chlamydial infection of the neck of the womb (cervicitis) is a sexually transmitted infection ... The infection can be passed through vaginal, anal, or oral sex." Is this true? Infection of the cervix is systemic, affecting the mucus of the rectum, and so fucking her in the ass can pass the infection? I think the sentence was misplaced from elsewhere in the article.98.111.146.18 (talk) 10:16, 8 November 2012 (UTC)
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Section: Epidemiology
Figure: Age-standardized death from chlamydia per 100,000 inhabitants in 2004
The bit "death from chlamydia per 100,000 inhabitants" is AWFULLY WRONG as the original data source clearly states it's DALYs and not deaths -DALY is "disability-adjusted life year"-
I'm asking the figure and references to be deleted as I fail to see how an editor might manage to get some useful, clear and short explanation using DALY to match the level of the article.
[English is not my first language]
186.137.164.45 (talk) 16:24, 14 January 2014 (UTC)
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Hi, I think there should be a mention of and a link to freetest.me which is a service launched in 2008 in the UK to request free Chlamydia postal tests (home sampling lab tests). It's free and funded by the NHS and now tests over 100,000 patients annually. This would be relevant to UK visitors, and may be of interest to others. Deggle (talk) 21:19, 26 October 2015 (UTC)
Given I believe it's the only large-scale postal screening service of it's nature in the world, I think it is notable internationally (even if it's only available for the UK). There would be an argument for growth of remote screening of this nature to have a section or at least mention in itself. Around 5-10% of all UK screening (including those done in GUM clinics, GPs etc) are done via the freetest.me service. Deggle (talk) 22:08, 28 October 2015 (UTC)
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For sexually active women who are not pregnant, screening is recommended in those under 25 and others at risk of infection.[1] Risk factors include a history of chlamydial or other sexually transmitted infection, new or multiple sexual partners, and inconsistent condom use.[2] The Faculty of Sexual and Reproductive Healthcare (FSRH) Clinical Guidance recommends that 100% of women attending for emergency contraceptive are offered the opportunity for Chlamydia testing, because studies showed up to 9.1% of women aged <25 years presenting for emergency contraceptive had Chlamydia trachomatis.Yeung E, Comben E, McGarry C, Warrington R. (2015). "STI testing in emergency contraceptive consultations". British Journal of General Practice. 65 (631): 63. doi:10.3399/bjgp15X683449. PMID 25624285.((cite journal))
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References
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Wongplusma (talk) 04:46, 8 November 2015 (UTC)
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Please change "Chlamydia can be transmitted during vaginal, anal, or oral sex. Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth." To "Chlamydia can be transmitted during vaginal, anal, or oral sex. Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth. This can cause an eye infection or pneumonia in the new born. Having chlamydia may also make it more likely to deliver the baby too early." http://www.cdc.gov/std/Chlamydia/STDFact-Chlamydia.htm 173.168.8.203 (talk) 22:21, 26 April 2016 (UTC)
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In “Prevention” (in the intro, before the table of contents), I would like to change “having sex with one other person who is not infected” to “only having sex with people that are not infected”. The way it is currently written makes it sound as if having sex with a non-infected partner magically protects you.
178.83.188.253 (talk) 22:41, 26 June 2016 (UTC)
I know that both Chlamydia infection and Lymphogranuloma venerum are both caused by Chlamydia trachomatis, and I know they are separate diseases. If I remember right it is because of a difference in serotypes, but it is not clear in the article. I was wondering if someone who knows the topic better can flesh that part out. Thanks, D.c.camero (talk) 17:48, 11 February 2018 (UTC)
The result of the move request was: Moved per consensus. (non-admin closure) – Ammarpad (talk) 11:37, 9 August 2019 (UTC)
Chlamydia infection → Chlamydia – The namespace gonorrhea infection redirects to Gonorrhea (because the condition of being infection with gonorrhea is called "gonorrhea");likewise, the namespace for HIV infection is a redirect to the article on HIV/ AIDS; we do not have an article called syphilis infection, we have one called syphilis; we do not have an article called Polio infection, we have one called Polio. I think that the "infection" part is a kind of unnecessary disambiguation and should simply be dropped. I haven't seen any substantive discussion of this on the talk page, but prefer opening up a discussion rather than simply moving the article myself. A loose necktie (talk) 11:13, 2 August 2019 (UTC)
This article has multiple paragraphs where several sentences in a row all have the same reference at the end. This is unnecessary - one reference can apply for several consecutive sentences, as WP:CITEDENSE makes clear. It also makes the text very uninviting to read, constantly and unnecessarily punctuated with those reference links. I attempted to correct one paragraph, only to have a user undo me. How do others feel about this use? --Nat Gertler (talk) 01:41, 20 September 2019 (UTC)
The third sentence of the introduction now reads: "When symptoms do appear in can be several weeks after infection". The "in" should of course be "it". 77.164.133.132 (talk) 15:35, 6 July 2020 (UTC)
The intro mentioned 50-70 percent of women don't have any symptoms. One paragraph below that, "Silent epidemic" because 70_80 percent are asymptomatic. (Inconsistent)
Urinary urgency: urge to urinate more than often? Urge to urinate( urgency) Urinate more than often (frequency) Professor Fox & Dr B (talk) 10:27, 28 December 2020 (UTC)
https://sti.bmj.com/content/87/Suppl_1/A175.2
July 2011.
Title: P1-S5.02 Towards more robust estimates of the per sex act transmission probability of Chlamydia trachomatis
Results: The data showed similar proportions of infected female partners of infected men and infected male partners of infected women, suggesting similar transmission probabilities. Assuming an average infectious duration of 12 months for women and men, we obtained best-fit estimates for the transmission rate (0.0064 per day) and average duration of partnerships (6.0 months) in the study. The transmission rate per day corresponds to a per sex act transmission probability of 4.5%, assuming one unprotected episode of coitus per week in a partnership. Our analysis also shows that these estimates depend on the assumed infectious duration of chlamydia.
...
https://sti.bmj.com/content/95/2/115
March 2019.
Title: Does infection with Chlamydia trachomatis induce long-lasting partial immunity? Insights from mathematical modelling
Results: Partial immunity against reinfection was found necessary to explain observed C. trachomatis prevalence patterns by age and sexual risk. The reduction in susceptibility to reinfection was estimated at 93% using UK data (95% uncertainty interval (UI)=88%–97%) and at 67% using US data (95% UI=24%–88%). The model-structure sensitivity analyses affirmed model predictions. The immunity-mechanism sensitivity analyses suggested a mechanism of susceptibility reduction against reinfection or a mechanism of infectious-period duration reduction upon reinfection.
Conclusions: A strong long-lasting partial immunity against C. trachomatis reinfection should be present to explain observed prevalence patterns. The mechanism of immunity could be either a reduction in susceptibility to reinfection or a reduction in duration of infection on reinfection. C. trachomatis infection appears to naturally elicit a strong long-lasting immune response, supporting the concept of vaccine development.
...
STI / STD testing is probably never 100% accurate, so please retest some time later if you are in high risk.
--ee1518 (talk) 21:25, 7 November 2021 (UTC)
In other news, prevention of cholera is by not eating and prevention of covid is by not breathing. The description of prevention should include reasonable and likely measures, not absurdly exaggerated recommendations that the religious Right has formulated in hopes of scaring whatever teenager happens to read this page into never having sex and becoming a monk or a nun. --178.249.169.67 (talk) 06:15, 28 January 2022 (UTC)
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Chlamydia can be spread during vaginal, anal, or [[oral sex]
PLease remove the porn images from these descriptions. They are highly offensive and not appropriate because there is no age restriction attached to wikipedia usage. I look forward to your positive response.
)) GenevaJones (talk) 04:00, 14 February 2022 (UTC)
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template. Please see WP:NOTCENSORED. ScottishFinnishRadish (talk) 04:18, 14 February 2022 (UTC)I think we should revert this edit, as the CDC explicitly mentions monogamous relationships, or if not changing it to another high quality source that mentions non-monogamous relationships. Uwsi (talk) 19:26, 26 February 2022 (UTC)
Chlamydia, which originated in the body of a female known as Josie Greiner, is one of the most powerful STDs known to man. 2600:1014:B131:2186:5A5:98E1:CBA:B658 (talk) 00:41, 8 April 2022 (UTC)
This article was the subject of a Wiki Education Foundation-supported course assignment, between 22 August 2023 and 11 December 2023. Further details are available on the course page. Student editor(s): 60shots (article contribs). Peer reviewers: Brownpaylon7, Cardiothoracics.
— Assignment last updated by Mbl5581 (talk) 17:00, 3 October 2023 (UTC)