Southerland may refer to:

• James Southerland, American professional basketball player
• Pug Southerland (1911-1949), American Navy fighter pilot during World War II
• Steve Southerland (Tennessee politician) (born 1955), member of the Tennessee House of Representatives
• Steve Southerland (Florida politician) (born 1965), United States Representative for Florida's 2nd District
• Thom Southerland, English theatre director
• William Henry Hudson Southerland (1852–1933), rear admiral in the United States Navy

• USS Southerland (DD-743), a Gearing-class American destroyer
• Fort Southerland, Arkansas site of a Civil War engagement, part of the Camden Expedition
• Highland Clearances, also known as Southerland Clearances, or the "expulsion of the Gael"), the forced displacement of a significant number of people in the Scottish Highlands during the 18th and 19th centuries, as a result of an agricultural revolution

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