Ohanyan or Ohanian (Armenian: Օհանյան, Western Armenian Օհանեան) is a common Armenian surname.

Ohanian

• Alexis Ohanian (born 1983), American internet entrepreneur, activist and investor and co-founder of the social news website Reddit and more recently the husband of American female tennis player Serena Williams
• Armen Ohanian (1887–1976), Armenian dancer, actress, writer, and translator
• Lee E. Ohanian (born 1957), macroeconomist and university lecturer
• Melik Ohanian (born 1969), French contemporary artist
• Ovanes Ohanian (1896–1960), Armenian-Iranian filmmaker, inventor, founder, doctor, scientist
• Raffi Ohanian (born 1989), Armenian singer, winner of 2009-2010 season of Hay Superstar
• Vartine Ohanian (born 1984), Lebanese politician of Armenian descent

Ohanyan

• Seyran Ohanyan, (born 1962), Armenian politician and minister