Never Give Up may refer to:

Film and television

• Never Give Up (1934 film), a Chinese film of the 1930s
• Never Give Up (1978 film), a Japanese film
• Never Give Up: The 20th Century Odyssey of Herbert Zipper, a 1995 documentary film
• Vai na Fé, a 2023 Brazilian telenovela, also titled Never Give Up

Songs

• "Never Give Up" (Sia song), 2016
• "Never Give Up" (Maria Sur song), 2023
• "Never Give Up (Party Party)", by Paul Haig, 1983
• "Never Give Up", by A. R. Rahman from the Million Dollar Arm film soundtrack, 2014
• "Never Give Up", by Barbra Streisand from Guilty, 1980
• "Never Give Up", by Fantastic Negrito from Please Don't Be Dead, 2018
• "Never Give Up", by Jodi Benson and Samuel E. Wright from the TV series The Little Mermaid, 1993
• "Never Give Up", by Keke Wyatt from Who Knew?, 2010
• "Never Give Up", by New Found Glory from Sticks and Stones, 2002
• "Never Give Up", by Rage from Gib dich nie auf, 2009
• "Never Give Up", by Room 2012, 2007
• "Never Give Up", by Yolanda Adams from Believe, 2001

Other uses

• Never Give Up (video game), a 2019 2D platform game
• Never Give Up!, a 1999 Japanese comic for girls by Hiromu Mutou
• Never Give Up: My Stroke, My Recovery, and My Return to the NFL, a 2007 book by Tedy Bruschi
• Never Give Up: How I Turned My Biggest Challenges into Success, a 2008 book by Donald Trump