MicC RNA | |
---|---|
Identifiers | |
Symbol | MicC |
Alt. Symbols | IS063 |
Rfam | RF00121 |
Other data | |
RNA type | Gene; sRNA |
Domain(s) | Bacteria |
SO | SO:0000655 |
PDB structures | PDBe |
The MicC non-coding RNA (previously known as IS063 [1]) is located between the ompN and ydbK genes in E. coli. This Hfq-associated RNA is thought to be a regulator of the expression level of the OmpC porin protein, with a 5′ region of 22 nucleotides potentially forming an antisense interaction with the ompC mRNA. Along with MicF RNA this family may act in conjunction with EnvZ-OmpR two-component system to control the OmpF/OmpC protein ratio in response to a variety of environmental stimuli.[2] The expression of micC was shown to be increased in the presence of beta-lactam antibiotics.[3]