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Mendefera Subregion is a subregion in the Debub (Southern) region (Zoba Debub) of Eritrea. Its capital lies at Mendefera.

References

v t e Subregions of Eritrea by region
Capital: Asmara
Anseba Region	Adi Tekelezan Asmat Elabared Geleb Hagaz Halhal Habero Keren Kerkebet Sela
Maekel Region (Central)	Berikh Ghala Nefhi North Eastern North Western Serejaka South Eastern South Western
Gash-Barka Region	Akurdet Barentu Dghe Forto Gogne Haykota Logo Anseba Mensura Mogolo Molki Omhajer Shambuko Tesseney Upper Gash
Northern Red Sea Region	Afabet Dahlak Ghelalo Foro Ghinda Karura Massawa Nakfa She'eb
Debub Region (Southern)	Adi Keyh Adi Quala Areza Debarwa Dekemhare Kudo Be'ur Mai-Mne Mendefera Segheneyti Senafe Tserona
Southern Red Sea Region	Are'eta Central Denkalya Southern Denkalya
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