Manasseh (Hebrew: מְנַשֶּׁה, Modern: Menaše, Tiberian: Mənaššé) is both a given name and a surname. Its variants include Manasses and Manasse.

Notable people with the name include:

Surname

• Ezekiel Saleh Manasseh (died 1944), Singaporean rice and opium merchant and hotelier
• Jacob Manasseh (died 1832), Ottoman rabbi
• Leonard Manasseh (1916–2017), British architect
• Maurice Manasseh (born 1943), English cricketer

Given name

• Manasseh (tribal patriarch), first son of Joseph
• Manasseh of Judah, king of Judah in the 7th century BC
• Manasseh II, hypothetical Jewish ruler of the Khazars in the 9th century AD
• Manasseh Azure, freelance journalist in Accra, Ghana
• Manasseh Masseh Lopes (1755–1831), British politician
• Manasseh Magok Rundial, South Sudanese politician
• Manasseh Sogavare (born 1955), Solomon Islands politician and Prime Minister
• Manasseh Kumardas Florentine (born 2007), entrepreneur

Fictional characters

• Manassseh da Costa, The King of Schnorrers