Protein-coding gene in the species Homo sapiens
Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene.[5][6][7][8]
MTCH2 resides on the outer mitochondrial membrane where it co-localizes with the apoptotic Bcl-2 family protein BID.[9]
Clinical significance
MTCH2 assists in the recruitment of BID into the mitochondria during apoptosis.[9]
Variants of the MTCH2 gene may be associated with obesity.[10] MTCH2 represses mitochondrial metabolism such that a deficiency of MTCH2 increases energy consumption and production by mitochondria.[9]