This is current list of comic science fiction, mixing science fiction or science fantasy with comedic intent.

• Douglas Adams' Hitchhiker's Guide to the Galaxy and related novels
• Robert Asprin's Phule series
• Fredric Brown's Martians, Go Home and other novels and short works.
• Most of Ron Goulart's work
• Rob Grant and Doug Naylor's Red Dwarf
• Harry Harrison's Stainless Steel Rat and Star Smashers of the Galaxy Rangers novels
• Simon Haynes's Hal Spacejock novels
• Eric Idle's The Road to Mars
• Stanislaw Lem's novel Cyberiad and his Ijon Tichy stories.
• Paul Levinson's short story "Extra Credit"
• Much of Robert Sheckley's work
• Kurt Vonnegut's novel The Sirens of Titan, and a lot of his work
• Snoo Wilson's novel Spaceache
• The novels of Rob Grant (Colony, Incompetence and Fat).
• Rob Reid's Year Zero
• John Scalzi's Redshirts: A Novel with Three Codas
• D. Harlan Wilson's novels Dr. Identity and Codename Prague
• Steven Erikson's Willful Child

• Visit to a Small Planet (1960)
• The Nutty Professor (1963)
• Los astronautas (1964, Spanish)
• Il disco volante (1964, Italian)
• Barbarella (1968)
• Fancy Paradise (1968, Japanese)
• Sleeper (1973)
• Dark Star (1974)
• The Cat from Outer Space (1978)
• Slapstick of Another Kind (1982/1984)
• The Adventures of Buckaroo Banzai Across the 8th Dimension (1984)
• The Ice Pirates (1984)
• Surf II (1984)
• Back to the Future trilogy (1985–1990)
• Weird Science (1985)
• Dr. Otto and the Riddle of the Gloom Beam (1986)
• Short Circuit (1986)
• Flight of the Navigator (1986)
• The Pink Chiquitas (1987)
• Spaceballs (1987)
• *batteries not included (1987)
• Short Circuit 2 (1988)
• Mom and Dad Save the World (1992)
• Space Truckers (1996)
• Mars Attacks! (1996)
• Men in Black trilogy (1997–2012)
• Galaxy Quest (1999)
• My Favorite Martian (1999)
• The Nutty Professor II: The Klumps (2000)
• Cybermutt (2002)
• The Adventures of Pluto Nash (2002)
• Good Boy! (2003)
• Mutant Swinger from Mars (2003/2009)
• Zathura (2005)
• The Hitchhiker's Guide to the Galaxy (2005)
• Idiocracy (2006)
• Frequently Asked Questions About Time Travel (2009)
• Land of the Lost (2009)
• Hot Tub Time Machine (2010)
• Paul (2011)
• Iron Sky (2012)
• John Dies at the End (2012)
• The Watch (2012)
• Big Ass Spider! (2013)
• The World's End (2013)
• Nambiar (2013)
• Mr. Peabody & Sherman (2014)
• Big Hero 6 (2014)

• Giants: Citizen Kabuto
• Ratchet & Clank series
• Space Quest series
• MDK2
• Leather Goddesses of Phobos
• EarthBound series
• Portal series
• Day of the Tentacle
• Borderlands series

• Red vs. Blue (2003–present)

• My Favorite Martian (1963-1966)
• Quark (TV series) (1977-1978)
• "The Worm That Turned" serial series of sketches from Series 8 of The Two Ronnies (1980)
• Mystery Science Theater 3000 (1988–1999)
• Red Dwarf (1988–1999, 2009, 2012-)
• The Grim Adventures of Billy & Mandy (2003-2008)
• Courage the Cowardly Dog (1995, 1999-2002) (also contains elements of fantasy and horror)
• 3rd Rock from the Sun (1996–2001)
• Dexter's Laboratory (1996-2003)
• Futurama (1999–2003, 2008–2013)
• Invader Zim (2001-2002, 2006)
• Time Squad (2001-2003)
• Clone High (2002-2003)
• The Adventures of Jimmy Neutron: Boy Genius (2002-2006)
• Hyperdrive (2006-2007)
• Phineas and Ferb (2007-2015)
• Robotomy (2010)
• Quantum Leap (1989-1993)
• Steven Universe (2013-)
• Rick and Morty (2013-)

There are also any number of animated Japanese series which use a scifi-comedy or scifi-fantasy-comedy setting. Urusei Yatsura, Dr. Slump, FLCL and Tenchi Muyo! are examples.

• The Crew (webseries) (2008–present)
• Voyage Trekkers (2011–present)
• Other Space (2015–present)

• Starslip Crisis (2005–present)
• Schlock Mercenary (2000–present)

• Hitchhiker's Guide to the Galaxy (radio series) (1978-2005)
• Canadia: 2056 (2007–present)
• Nebulous (2005-2008)
• Space Hacks (2007-2008)
• The Spaceship (2005-2008)
• Undone (2006-2010)

• Ruby the Galactic Gumshoe (1982–present)

• Steve Jordan's play 'Dead Static' and its sequel 'Pilgrim Shadow'.

• Back to the Future series by Robert Zemeckis (feature films, novelizations, animated TV series and video games)
• Douglas Adams's The Hitchhiker's Guide to the Galaxy series (radio, printed novels, TV series, feature film, etc.)
• Hyper Police series by Minoru Tachikawa (manga and anime).
• Gin Tama series by Hideaki Sorachi (manga and anime).

• Comic fantasy