Drug films are films that depict either drug distribution or drug use, whether as a major theme or in a few memorable scenes. Drug cinema ranges from the ultra-realistic to the utterly surreal; some films are unabashedly pro- or anti-drug, while others are less judgmental. The drugs most commonly shown in films are cocaine, heroin, LSD, cannabis (see stoner film) and methamphetamine.

There is extensive overlap with crime films, which are more likely to treat drugs as plot devices to keep the action moving.

The following is a partial list of drug films and the substances involved.

0–9

• 1. Mai – Helden bei der Arbeit - MDMA
• 21 Grams (2003) - cocaine
• 21 Jump Street (2012) - HFS (a fictional drug), marijuana
• 22 Jump Street (2014) - WHYPHY (a fictional drug)
• 24 Hour Party People (2002) - MDMA, cocaine, heroin, methadone, cannabis, and a mention of the large amount of crack in Barbados
• 25th Hour (2002) - heroin, MDMA
• 28 Days (2000) - prescription drugs, heroin, alcohol
• 28 Days Later (2002) - prescription drugs (Valium)
• 30 Minutes or Less (2011) - cannabis
• The 40-Year-Old Virgin (2005) - cannabis
• 50/50 (2011) - cannabis
• The 51st State (2001) - POS 51 (a fictional drug); mentions cocaine, LSD and MDMA
• 54 (1998) - marijuana, cocaine, MDMA, Quaaludes^[1]
• 9 (2009) - Magnet (a fictional drug), used by 8 which causes a drug-like effect
• 99 Francs (2007) - cannabis, cocaine

A

• The Acid House (1998) - LSD, cannabis, poppers
• Across The Universe (2007) - LSD, cannabis, some kind of opiate (presumably morphine)^[2]
• Acts of Worship (2001) - heroin, crack cocaine
• Adam & Paul (2003) - heroin, cannabis
• Adaptation. (2002) - fictional version of ghost orchid powder
• Adulthood (2008) - cannabis, cocaine
• Adventureland (2009) - cannabis
• Air America (1990) - heroin, opium
• Airplane! (1980) - cocaine, glue, amphetamine
• Alice in Acidland (1969) - LSD
• Alice (1988) - Amanita muscaria
• Almost Famous (2000) - cannabis, Vicodin, LSD and Quaaludes
• Alpha Dog (2007) - cannabis
• Altered States (1980) - cannabis, Amanita muscaria, LSD, DMT, and psilocybin
• American Beauty (1999) - cannabis
• American Cowslip (2009) - heroin
• American Gangster (2007) - heroin and cocaine
• American Psycho (2000) - cocaine, Halcion, Xanax, ecstasy and cannabis
• American Ultra (2015) - cannabis
• American Virgin (2009) - cannabis, unspecified drugs
• Amores Perros (2001) - cocaine
• Analyse That (2002) - cocaine
• Animal Kingdom (2010) - cannabis, cocaine, heroin
• The Anniversary Party (2001) - MDMA
• Annie Hall (1977) - cocaine
• Another Day in Paradise (1997) - heroin, references to meth and cocaine^[1]
• Another Happy Day (2011) - fentanyl
• Apocalypse Now (1979) - marijuana, LSD, and opium
• Around the Fire (1999) - cannabis, LSD
• Arrebato (1979) - heroin, cocaine and amyl nitrite
• Assassin of Youth (1937) - cannabis^[3]
• At Close Range (1986) - marijuana
• Attack the Block (2011) - cannabis, crack/cocaine
• Avenging Disco Godfather (1979) - PCP
• Awakening of the Beast (1970, aka O Ritual dos Sádicos and O Despertar da Besta) - LSD
• Awaydays (2009) - cocaine, cannabis and heroin

B

• Babel (2006) - MDMA and opium
• Bad Batch (2010) - marijuana and cocaine
• Bad Boys (1995) - heroin
• Bad Boys II (2003) - MDMA and heroin
• Bad Lieutenant (1992) - crack, cocaine, heroin and cannabis
• Bad Moms (2016) - cannabis
• Bad Teacher (2011) - cannabis
• The Ballad of Little Jo (1993) - opium
• Bang Boom Bang (1999) - cannabis
• Bangkok Hilton (1989) - heroin
• Basic Instinct (1992) - cocaine
• The Basketball Diaries (1995) - heroin, cocaine, cannabis, solvents and various pills^[4]
• Batman Begins (2005) - a fictional hallucinogenic gas
• Be.Angeled (2001) - cocaine, MDMA and cannabis
• The Beach (2000) - cannabis, psychedelic mushrooms and stimulants
• The Beach Girls (1982) - marijuana and unidentified pills
• Beavis and Butt-head Do America (1996) - peyote^[2]
• Beerfest (2006) - cannabis
• Before the Devil Knows You're Dead (2007) - heroin (IV) and cocaine
• Before I Disappear (2014) - heroin, pills
• Belly (1998) - heroin, cannabis
• Berkeley in the Sixties (1990)^[1]
• Berlin Calling (2008) - cocaine, MDMA, MDA, PMA, ketamine, cannabis; mentions LSD and methamphetamine
• Better Living Through Chemistry (2014) - pharmaceutical mixing and abuse
• La Beuze (2003) - chemical cannabis made by Nazis during WWII which gives users hallucinations of football players
• Beyond the Valley of the Dolls (1970) - cannabis, LSD, prescription pills, MDMA, peyote
• The Big Bang (2010) - Valium, methampthetamine
• The Big Boss (1971) - heroin
• The Big Chill (1983) - cannabis, cocaine
• The Big Easy (1987) - heroin
• The Big Lebowski (1998) - cannabis, LSD
• Bigger Than Life (1956) - cortisone (steroid hormone)
• Bird (1988) - heroin
• Black's Game (2012) - speed, MDMA, cocaine
• Black Cat, White Cat (1998) - cocaine
• Black Fear (1915) - cocaine
• Black Snake Moan (2006) - prescription pills, ecstasy
• Black Swan (2010) - ecstasy
• Black Tar Heroin (1999) - black tar heroin, crack cocaine, methamphetamine, alcohol
• Blazing Saddles (1974) - cannabis
• The Bling Ring (2013) - marijuana, cocaine, heroin (smoked)
• Blood In Blood Out (1993) - cocaine and heroin
• Blow (2001) - cocaine and cannabis^[1]
• Blue Sunshine (1976) - LSD
• Blue Velvet (1986) - nitrous oxide
• Blueberry (2004) - ayahuasca, peyote
• Bobby (2006) - LSD
• Bodies, Rest & Motion (1993) - marijuana
• Boiler Room (2000) - cocaine
• Bonded by Blood (2010) - cocaine, ecstasy
• Bongwater (1997) - cannabis, LSD, and cocaine
• Boogie Nights (1997) - cannabis, cocaine and methamphetamine
• Boondock Saints (1999) - cocaine
• The Boost (1988) - cocaine
• Borderland (2007) - cannabis and psychedelic mushrooms
• Borderline (1950) - drugs not identified
• The Boys & Girls Guide to Getting Down (2006) - cannabis, MDMA, cocaine, crack, heroin, amphetamine, Viagra
• The Boys in the Band (1970) - cannibas
• Boys Don't Cry (1999) - cannabis
• The Boys in Company C (1978) - Demerol and heroin^[5]
• Brain Candy (1996) - fictional drug GLeeMONEX
• The Breakfast Club (1985) - cannabis
• Brick (2006) - heroin
• Bright Lights, Big City (1988) - cocaine
• Britannia Hospital (1982) - psilocybin mushrooms
• Brokedown Palace (1999) - heroin
• Broken (2007) - heroin
• Broken Vessels (1999) - heroin, methamphetamine
• A Bucket of Blood (1959) - heroin
• Buffalo Soldiers (2001) - heroin, MDMA
• Bug (2006) - methamphetamine, cannabis
• A Bug and a Bag of Weed (2006) - cannabis, hashish
• Bullet (1996) - heroin
• Bully (2001) - cannabis, LSD, methamphetamine
• The Business (2005) - cannabis, MDMA, cocaine

C

• Caddyshack (1980) - marijuana
• Candy (2006) - heroin, cannabis
• Candy Stripe Nurses (1974) - marijuana, amphetamines^[6][7]
• Carlito's Way: Rise to Power (2005) - heroin
• Cartoon All-Stars to the Rescue (1990 TV special) - marijuana and crack
• Cash Crop (2003) - cannabis
• Casino (1995) - cocaine, heroin and painkillers
• Cass (2008) - cannabis
• Caveman (1981) - fictional hallucinogenic berries
• Cecil B. Demented (2000) - heroin
• Chappaqua (1966) - peyote and heroin
• Charlie Bartlett (2008) - prescription pills
• Cheech & Chong's various films feature drugs such as cannabis, cocaine, LSD, peyote and various pills and Ajax (comedy). They include:
  • Up in Smoke (1978)^[8]
  • Cheech & Chong's Next Movie (1980)
  • Nice Dreams (1981)
  • Things Are Tough All Over (1982)
  • Still Smokin' (1983)
• Cherry Falls (2000) - marijuana
• Cherry, Harry & Raquel! (1970) - cannabis
• Cherrybomb (2009) - cannabis, cocaine and ecstasy
• Chinatown Nights (1929) - opium
• Chinese Opium Den (1894) - opium
• Chopper (2000) - cocaine, heroin (and possibly amphetamines)
• Christiane F. – Wir Kinder vom Bahnhof Zoo (1981) - cannabis, LSD, heroin, various pills such as Valium and Mandrax
• The City Addicted to Crystal Meth (2009) - crystal meth (methamphetamine)
• City by the Sea (2002) - crack
• City Of God (2002) - cannabis, cocaine
• Clean and Sober (1988) - cocaine^[1]
• Clerks (1994) - cannabis
• Clockers (1995) - crack cocaine
• A Clockwork Orange (1971) - several fictional drugs in the form of a milk cocktail called Moloko Plus; varieties include Moloko Vellocet, either an opiate (percocet) or an amphetamine (velocity, speed), Synthemesc (synthetic mescaline), and Drencrom (adrenochrome)
• Club Paradise (1986) - cannabis
• Clubbed to Death (1996) - MDMA
• Clueless (1995) - cannabis, cocaine
• Cocaine Cowboys (2006) - cocaine and cannabis
• Cocaine Cowboys 2 (2008) - cocaine
• Cocaine: One Man's Seduction (1983) - cocaine
• Cocksucker Blues - cocaine and heroin
• Code of Silence (1985) - cocaine
• Colors (1988) - marijuana, crack cocaine and PCP
• Conspiracy Theory (1997) - LSD
• Contact High (2009) - cocaine, cannabis, MDMA, LSD, amphetamine
• Contraband (2012) - cocaine
• Coogan's Bluff (1968) - marijuana and LSD
• Cookers (2001) - methamphetamine
• The Cool and the Crazy (1958) - cannabis
• Coonskin (1975) - LSD, heroin
• Cop Out (2010) - crack/cocaine, mescaline (referred to)
• Corridors of Blood (1958) - opium-based anaesthetic
• Country Man (1982) - cannabis
• Crank (2006) - fictional drug "Beijing Cocktail", cocaine, epinephrine, "Hardcore Haitian Plant Shit" (which probably refers to khat), methamphetamine, cannabis
• Crooklyn (1994) - glue (toluene)
• Crossing the Bridge (1992) - heroin
• The Crow (1994) - morphine
• Cruel Intentions (1999) - cocaine (memorably taken out of a rosary necklace)
• Crystal Fairy & the Magical Cactus (2012) - mescaline

D

• Danger Diabolik (1968) - cannabis
• Darwin's Nightmare (2004) - glue (Toluene)
• The Day of the Beast (1995) - LSD
• Daymaker (2007) - cocaine, MDMA, LSD, cannabis
• Dazed and Confused (1993) - alcohol, cannabis, LSD^[2]
• Dead Presidents (1995) - Heroin, morphine
• Dead Man's Shoes (2004) - cocaine, cannabis, LSD, MDMA
• Dead Ringers (1988) - various prescription drugs (dextroamphetamine and opioids)
• Death at a Funeral (2010) - mescaline, Valium and ketamine (mentioned), acid (the pills in the Valium bottle)
• The Death of Richie (1977) - barbiturates and other drugs
• Death Wish 2 (1982) - marijuana and PCP
• Death Wish 4: The Crackdown (1987) - crack cocaine
• The Decline of Western Civilization Part II: The Metal Years^[2]
• Deep Cover (1992) - crack cocaine
• Delta Force 2: The Colombian Connection (1990) - cocaine
• Den Siste Revejakta (2008) - hashish, cannabis, heroin and LSD
• The Departed (2006) - Oxycontin, lorazepam, heroin and cocaine
• Detroit Rock City (1999) - cannabis and psychedelic mushrooms
• Dev.D (2009) - cocaine, LSD, ecstasy and various pills
• Devil's Harvest (1942) - cannabis
• The Devil's Rejects (2005) - cannabis
• Dick (1999) - cannabis and Quaaludes
• District 13 (2004) - cocaine, cannabis
• Domino (2005) - mescaline, cannabis, and cocaine
• Donkey Punch (2008) - ketamine, Methamphetamine, MDMA, cannabis
• Don's Plum (2001) - heroin, cannabis
• Don't Be a Menace to South Central While Drinking Your Juice in the Hood (1996) - marijuana and crack cocaine
• Don't Tell Mom the Babysitter's Dead (1991) - cannabis
• The Doors (1991) - LSD, cocaine, heroin, cannabis and peyote
• Dope Sick Love (2005) - heroin and crack cocaine
• Down in the Valley (2005) - MDMA
• Dragon Eyes (2012) - crack, heroin
• Dream with the Fishes (1997) - heroin and LSD
• Dreamseller (2007) - heroin
• Dredd (2012) - fictional drug Slo-mo (slows the user's perception to 1%)
• The Drug Traffic (1923)
• Drugstore Cowboy (1989) - hydromorphone, oxymorphone, morphine, amphetamines, diazepam, methamphetamine, and heroin^[1]
• Dude, Where's My Car? (2000) - cannabis
• Due Date (2010) - cannabis and vicodin
• The Dukes of Hazzard (2005) - marijuana
• Dune (1984) - fictional drug Melange or "Spice"

E

• Easy A (2010) - cannabis
• Easy Rider (1969) - cannabis, cocaine and LSD^[1]
• Easy Street (1917) - cocaine
• Ecstasy (2011) - Little Red Pill
• ed! (1996) - cannabis, MDMA
• Ed Wood (1994) - morphine
• Eden Lake (2009) - amyl nitrate
• Elephant White (2011) - heroin
• Emerald Forest (1985) - Virola snuff
• Empire (2002) - heroin and cannabis
• Empire Records (1995) - amphetamines
• Enter the Dragon (1973) - heroin
• Enter the Void (2009) - cocaine, LSD, GHB, cannabis, MDMA, methamphetamine, Datura, and DMT
• Equilibrium (2002) - fictional drug Prozium
• Essex Boys (2000) - MDMA, heroin
• Eternal Sunshine of the Spotless Mind (2004) - cannabis
• Euro Trip (2004) - cannabis/hashish, absinthe, amphetamines, benzedrine
• Even Cowgirls Get the Blues (1993) - peyote
• Everywhere and Nowhere (2011) - cannabis, cocaine, MDMA
• Evil Bong (2006) - cannabis
• Evil Bong 2: King Bong (2009) - cannabis
• The Expendables (2010) - cocaine
• Extract (2009) - ketamine, Xanax, various other drugs
• Eyes Wide Shut (1999) - cannabis, speedballs

F

• Factory Girl (2006) - cannabis, speed, heroin, prescription pills
• The Falcon and the Snowman (1985) - cocaine
• Fame chimica (2003) - cannabis and cocaine
• Fanboys (2009) - peyote
• Fandango (2000) - cannabis and cocaine
• Fast Times at Ridgemont High (1982) - cannabis
• Faster (2010) - heroin
• Fear and Loathing in Las Vegas (1998) - cannabis, mescaline, thorazine, LSD, cocaine, amphetamines, barbiturates, ether, amyl nitrite, opium, hashish, hash oil, heroin, adrenochrome^[8]
• Federal Fugitives (1941) - pills
• Fifty Pills (2006) - MDMA
• The Final Programme (1973)
• Flashback (1990) - LSD
• Flirting with Disaster (1996) - LSD
• Foo-Foo Dust (2003) - crack cocaine and heroin
• The Football Factory (2004) - cannabis, inhalants, amphetamines, crack/cocaine
• A Force of One (1979) - cocaine and heroin
• Formula 51 (2002) - fictional drug like ecstasy
• Forrest Gump (1994) - cocaine, heroin, cannabis, LSD, unidentified pills
• Freak Talks About Sex (1999) - cannabis
• Freebird (2008) - marijuana, psychedelic mushrooms^[9]
• Freddy's Dead: The Final Nightmare (1991) - marijuana
• The French Connection (1971) - heroin and cocaine
• French Connection II (1975) - heroin
• Fresh (1994) - cocaine, crack cocaine, heroin
• Friday (1995) - marijuana, PCP
• Friday After Next (2002) - cannabis
• Friday the 13th film series (1980–2009) - cannabis is smoked in most of the films
• Friday the 13th Part VIII: Jason Takes Manhattan (1989) - cocaine, heroin
• Fringe series - LSD, unidentified psychoactive drugs
• Fritz the Cat (1972) - cannabis and heroin
• From Hell (2001) - opium, laudanum and absinthe
• From Paris with Love (2010) - cocaine, possibly heroin

G

• Gambling, Gods and LSD (2002) - crack, cocaine, LSD
• Gangster Exchange (2011) - cannabis, MDMA, LSD, crack, heroin
• Garden State (2004) - cocaine, MDMA, marijuana, nitrous oxide, various prescription drugs (especially antidepressants)
• Georgia (1995) - heroin
• Get Him to the Greek (2010) - marijuana, absinthe, heroin, "Jeffrey", cocaine, adrenaline
• Get Out (2017) - marijuana^[10]
• Get Out and Get Under (1920) - cocaine
• Get Rich or Die Tryin' (2005) - crack, marijuana, and morphine
• Ghost in the Shell (2017) - marijuana
• Gia (1998) - heroin and cocaine
• Gift (1993)^[2]
• Girl, Interrupted (1999) - marijuana, diazepam
• The Girl Next Door (2004) - MDMA, marijuana
• Go (1999) - MDMA, marijuana and cocaine
• Go Ask Alice (1973) - LSD, marijuana, and amphetamines
• The Godfather (1972) - cocaine and heroin
• The Godfather Part II (1974) - cocaine and heroin
• The Godfather Part III (1990) - cocaine and heroin
• The Good Shepherd (2006) - LSD
• Goodfellas (1990) - cocaine and pills
• Goon (2011) - cannabis
• Gorp (1980) - amphetamines and Quaaludes
• Grand Hotel (1932) - absinthe
• Grandma's Boy (2006) - marijuana
• Grass (1999) - marijuana
• The Greatest (2009)
• The Green Butchers (2003) - marijuana
• The Green Hornet (2010) - methamphetamine
• Gridlock'd (1997) - heroin
• Grimsby (2016) - cocaine and heroin
• Grindhouse (2007) - marijuana
• Groove (2000) - GHB, MDMA, nitrous, LSD and marijuana
• The Groove Tube (1974) - marijuana
• The Guard (2011) - LSD, cocaine
• Gummo (1997) - glue, Ritalin, solvents, cocaine

H

• La Haine (1995) - marijuana, hashish, cocaine
• Hair (1978) - cannabis and LSD
• Half Baked (1998) - cannabis, cocaine, crack and heroin^[1]
• Half Nelson (2006) - cocaine and crack cocaine
• Hall Pass (2011) - marijuana (brownies)
• Halloween (1978) - marijuana
• The Hangover (2009) - GHB, rohypnol
• The Hangover 2 (2011) - cocaine
• The Hangover 3 (2013) - demerol, rohypnol, ecstasy
• Hannibal (2001) - chloroform, morphine (and unknown sedatives)
• Hard Ticket to Hawaii (1987) - marijuana
• Hardbodies (1984) - marijuana and cocaine
• Hare Rama Hare Krishna (1971) - cannabis resin
• Harold & Kumar Escape from Guantanamo Bay (2008) - cannabis, and psilocybin mushrooms
• Harold & Kumar Go to White Castle (2004) - cannabis, MDMA, cocaine
• Harold & Kumar: A Very Harold & Kumar 3D Christmas (2011) - cannabis, psilocybin extract, crack, ecstasy, cocaine
• Harry Brown (2009) - cannabis, crack/cocaine, heroin
• Harsh Times (2006) - cannabis
• Harvard Man (2001) - cannabis, LSD
• The Hasher's Delirium, aka Le songe d'un garçon de café (1910) - absinthe^[11]
• Havoc (2005) - cocaine, crack
• Head (1968) - cannabis, LSD^[2]
• Head, Heart and Balls... or Why I Gave Up Smoking Pot (2007) - marijuana ^[12]
• Heavy Metal (1981) - cannabis mentioned and fictional drug "Nyborg" - parody of cocaine
• The Heart Is Deceitful Above All Things (2004) - methamphetamine
• Hells Angels on Wheels (1967) - marijuana, amphetamines
• High Art (1998) - heroin^[1]
• High School Confidential (1958) - marijuana, heroin
• High School High (1996) - marijuana
• Hobo With A Shotgun (2011) - cocaine
• Hollywood High (2003)^[1]
• Holy Rollers (2010) - MDMA
• El hombre de los hongos, aka The Mushroom Man (1976) - psychedelic mushrooms
• A Home at the End of the World (2004) - cannabis, LSD
• Homegrown (1998) - cannabis
• La Horde (2010) - cocaine
• Horrible Bosses (2011) - cocaine and nitrous oxide
• Horrible Bosses 2 (2014) - nitrous oxide (laughing gas)
• Hot Rod (2007) - LSD
• Hot Tub Time Machine (2010) - cannabis, psilocybin mushrooms, cocaine
• How High (2001) - cannabis
• Howard Marks. Mr Nice (2010) - cannabis, LSD, opium
• Human Traffic (1999) - cannabis, cocaine and MDMA
• Human Wreckage (1923)^[1]
• Humboldt County (2008) - cannabis
• Hunt to Kill (2010) - methamphetamine
• Hurlyburly (1998) - cannabis, cocaine and diazepam
• Hustle & Flow (2005) - cannabis

I

• I Got The Hook Up (1998) - cannabis, cocaine and LSD
• I Love You, Alice B. Toklas (1968) - cannabis brownies
• I Love You Phillip Morris (2010) - heroin
• Idle Hands (1999) - cannabis
• If Drugs Were Legal (2009) - cannabis, cocaine, crack, ketamine, heroin, MDMA, LSD, amphetamines (and fictional drugs, including "dexclorazole," which mimics the effects of fluoxetine but on a much larger scale; and "xp25," which stimulates the serotonin neurotransmitters in the brain but causes sudden heart attack)
• Igby Goes Down (2002) - heroin, cannabis
• Ill manors (2012) - crack, cannabis
• Illtown (1998)^[1]
• I'm Dancing as Fast as I Can (1982) - Diazepam
• In Bruges (2008) - cocaine, ketamine, LSD, ecstasy
• In Vanda's Room (2000) - heroin
• Inauguration of the Pleasure Dome (1954) - ayahuasca
• Inherent Vice (2014) - cannabis
• Inner Trial (2008) - LSD, cannabis, psychedelic mushrooms
• An Innocent Man (1989) - cocaine
• Into the Blue (2005) - cocaine
• Iowa (2005) - manufacture and use of methamphetamine
• Irréversible (2002) - cocaine
• Irvine Welsh's Ecstasy (2011) - ecstasy, cannabis and cocaine
• It's All Gone Pete Tong (2004) - cocaine, yopo snuff, and toad licking, presumably a reference to the Bufo Alvarius or Colorado River toad from which the extract should not actually be licked as in the film, but smoked, due to bufo toxin which is incinerated upon smoking; can contain 5-meo-dmt and/or bufotenin

J

• Jackie Brown (1997) - cocaine, cannabis
• Jacob's Ladder (1990) - Quinuclidinyl benzilate (BZ)
• Janky Promoters (2009) - cannabis
• Jay and Silent Bob Strike Back (2001) - cannabis
• Jesus' Son (1999) - heroin, cannabis, cocaine, LSD, opium, psychedelic mushrooms, tobacco, amphetamines, and diazepam
• Jewel Robbery (1932) - cannabis
• Johnny Stecchino (1991) - cocaine
• Jubilee (1977) - Quaaludes
• Jungle Fever (1991) - heroin

K

• Ken Park (2002) - marijuana
• The Kentucky Fried Movie (1977) - heroin and opium
• Kid Cannabis (2014) - cannabis, cocaine, oxycodone
• Kids (1995) - marijuana, nitrous oxide, MDMA, cocaine and possibly GHB (not ketamine)
• Kidulthood (2006) - cannabis, cocaine, unknown pills
• Kill Bill: Vol. 2 (2004) - cocaine
• Killer Bud (2001) - marijuana
• Killing Zoe (1994) - heroin
• King of New York (1990) - cocaine
• Kinjite: Forbidden Subjects (1989) - marijuana, cocaine and heroin
• Kiss of the Dragon (2001) - heroin
• Knocked Up (2007) - marijuana and psychedelic mushrooms
• Kush (2007) - marijuana, cocaine

L

• Lady Sings The Blues (1972) - heroin
• Lammbock (2001) - marijuana, hashish, psychedelic mushrooms and cocaine
• The Last American Virgin (1982) - marijuana and cocaine
• The Last Days of Disco (1998)^[1]
• Last Life in the Universe (2003) - marijuana
• The Last Minute (2001) - heroin
• Layer Cake (2004) - cocaine, crack cocaine and MDMA
• Leaves of Grass (2009) - marijuana
• Leaving Las Vegas (1995) - alcohol
• Lenny (1974) - heroin
• Léon: The Professional (1994) - cocaine
• Leprechaun: Back 2 tha Hood (2003) - marijuana
• Less Than Zero (1987) - cocaine
• Lethal Weapon (1987) - cocaine and heroin
• Lethal Weapon 4 (1998) - nitrous oxide (laughing gas)
• Licence to Kill (1989) - cocaine
• The Life Aquatic with Steve Zissou (2004) - marijuana
• Life Is Hot in Cracktown (2009) - crack cocaine
• Light Sleeper (1992) - cocaine
• Lights in the Dusk (2006) - alcohol
• Limitless (2011) - fictional drug "NZT48"
• Liquid Sky (1982) - heroin
• Little Fish (2005) - heroin
• Little Miss Sunshine - heroin, Viagra and anorectics are referred to
• Little Shop of Horrors (1986) - nitrous oxide (laughing gas)
• Live and Let Die (1973) - heroin
• Live Nude Girls (1995) - marijuana
• Lock, Stock and Two Smoking Barrels (1998) - marijuana and cocaine
• Loft (2008) - cocaine
• London (2005) - cocaine and marijuana
• London Boulevard (2010) - cannabis, cocaine, opium
• Looking for Eric (2009) - marijuana
• Lord of War (2005) - cocaine and brown-brown
• Lords of Dogtown (2005) - marijuana
• The Loser Takes It All (2002) - alcohol
• Lost in Translation (2003) - marijuana, possibly other psychedelics
• Love. Blood. Kryptonite. (2008) - marijuana, cocaine
• Love Is The Drug (2006) - cocaine, prescription pills
• Love Liza (2002) - gasoline fumes
• LSD, Trip or Trap (1967) - LSD
• Lucy (2014) - fictional nootropic CPH4

M

• Macarthur Park (2001) - crack cocaine
• Machete (2010) - cannabis, methamphetamine
• Mafia! (1998) - cocaine
• Magic Trip (2011) - LSD, AMT, psychedelics
• Magnolia (1999) - cocaine, amphetamines (Dexedrine), morphine
• Magnum Force (1973) - heroin
• Malibu Beach (1978) - marijuana
• Malibu High (1979) - marijuana, cocaine
• Mallrats (1995) - cannabis
• Midnight Delight (2016) - cannabis
• The Man with the Golden Arm (1955) - heroin^[1]
• Mantis in Lace (1968) - LSD
• Marfa Girl (2012) - cannabis
• Maria Full of Grace (2004) - heroin
• Marihuana (1936) - cannabis
• Maryjane (1968) - cannabis and hashish
• Mask (1985) - unidentified drugs
• Max Payne (2008) - fictional drug Valkyrie
• McCabe & Mrs. Miller (1971) - opium
• McQ (1974) - heroin and cocaine
• MDMA (2010) - MDMA^[13]
• Mean Streets (1973) - heroin
• The Men Who Stare At Goats (2009) - steroids, LSD, cannabis, amphetamine
• Menace II Society (1993) - crack cocaine, heroin and cannabis
• Miami Vice (2006) - cocaine
• Middle Men (2009) - cocaine, barbiturates
• Midnight Cowboy (1969) - marijuana, unspecified hallucinogenic pills
• Midnight Express (1978) - hashish, LSD and cannabis
• A Midsummer Night's Rave (2002) - MDMA, cocaine
• Minority Report (2002) - fictional psychoactive drug "Clarity"
• Missing Link (1988) - unidentified plant
• Modern Times (1936) - cocaine
• Mondo Mod (1967) - cannabis
• Moneyz (2009) - cannabis, cocaine, heroin, methamphetamine, LSD
• Monkey on My Back (1957) - morphine
• More (1969) - cannabis, heroin, absinthe, Dexamyl (amphetamine-barbiturate), LSD, and a homemade concoction made from cannabis (resin), benzedrine, "red ibogaine", nutmeg and banana peel
• Morfiy (2008) - morphine
• Morning Patrol (1987) - alcohol
• La morte accarezza a mezzanotte (1972) - LSD
• Most High (2006) - cocaine and methamphetamine
• Mouth to Mouth (2005) - cannabis, many other drugs
• Mr. Nice (2010) - marijuana, hashish
• Munje! (2001) - cannabis
• My Name Ain't Johnny (2008) cannabis, mainly cocaine
• My Own Private Idaho (1991) - cocaine
• The Mystery of the Leaping Fish (1916) - cocaine, opium^[14]

N

• The Naked Gun (1988) - heroin
• Naked Lunch (1991) - heroin, cannabis, opiates, fictional hallucinogenic bug powder
• A Name for Evil (1973) - LSD
• Narc (2002) - heroin, cannabis and possibly cocaine^[1]
• National Lampoon's Animal House (1978) - cannabis
• National Lampoon's Totally Baked: A Potumentary (2006) - cannabis
• National Lampoon's Vacation (1983) - marijuana
• Natural Born Killers (1994) - magic mushrooms, other drugs suggested but not explicitly stated^[2]
• Neighbors (2014) - psychedelic mushrooms and cannabis brownies
• Neighbors 2: Sorority Rising (2016) - cannabis
• Never Die Alone (2004) - cocaine, heroin
• New Jack City (1991) - crack cocaine
• Next Day Air (2009) - cocaine, cannabis
• Next Friday (2000) - cannabis
• The Night Before (2015) - psychedelic mushrooms, cannabis, cocaine, heroin, several unidentified drugs
• A Nightmare on Drug Street (1989) - cocaine, unidentified pills
• A Nightmare on Elm Street 3: Dream Warriors (1987) - heroin
• Nil by Mouth (1997) - heroin
• The Nine Lives of Fritz the Cat (1974) - cannabis, hallucinogenic drugs
• Nine to Five (1980) - cannabis
• Nixon (1995) - prescription drugs
• No Country for Old Men (2007) - heroin
• Nordkraft (2005) - cannabis, cocaine, methadone, heroin
• North Dallas Forty (1979) - marijuana, cocaine and painkillers
• Notorious (2009) - cocaine, crack and cannabis
• Nowhere (1997) - cannabis and MDMA

O

• O (2001) - steroids, cocaine
• On the Road (2012) - cannabis, benzedrine, morphine and alcohol
• Once Upon a Time in America (1984) - opium
• One False Move (1992) - cocaine
• One Perfect Day (2004) - cannabis, painkillers, amphetamines and MDMA
• Ong-Bak (2008) - opium
• The Opium Eater (2011) - opium
• Orange County (2002) - amphetamines, painkillers, cannabis, MDMA
• The Other Guys (2010) - cannabis mentioned
• Over The Edge (1979) - cannabis and LSD
• Out of the Blue (1980)
• Outland (1981) - amphetamine-type drug
• Outside Providence (1999) - cannabis
• Oxy-morons (2010) - oxycotin, heroin, Vicidon^[15]

P

• The Pace That Kills (aka Cocaine Fiends) (1935) - cocaine
• Paid in Full (2002) - cocaine, crack and cannabis
• Pain and Gain (2013) - cocaine, ecstasy, Xylazine
• The Palermo Connection (1991) - all drugs are referred to
• The Panic in Needle Park (1971) - heroin
• Papillon (1973) - cocaine (coca leaves)
• Parked (2010) - heroin and cannabis
• Party Monster (2003) - crack/cocaine, heroin, MDMA, LSD, ketamine
• Pathology (2008) - methamphetamine
• PCU (1994) - cannabis^[1]
• Perfect High (2015) - hydrocodone, codeine, Oxycontin, heroin; Adderall and benzodiazepines are referred to
• Performance (1970) - psychedelic mushrooms^[2]
• Permanent Midnight (1998) - heroin and cocaine^[1]
• Photographing Fairies (1997) - fictional psychoactive flowers
• Pimp (2010) - cannabis, crack/cocaine, heroin is referred to
• Pineapple Express (2008) - cannabis, Oxycodone is referred to
• Piñero (2001) - heroin, cannabis, cocaine
• Pink Cadillac (1989) - methamphetamine
• Pink Flamingos (1972) - poppers; the Marbles are involved in a heroin ring in inner-city schools
• Pink Floyd The Wall (1982) - hashish; this film is often considered a drug-induced movie (LSD, psychedelics)
• Pirates of Silicon Valley (1999) - cannabis, LSD
• Platoon (1986) - cannabis, and opium
• Platoon Leader (1988) - heroin
• Playing God (1997) - fentanyl, morphine and amphetamines
• Poltergeist (1982) - cannabis
• Polvere (2009) - cocaine
• Possession (1981) - psilocybin mushrooms
• Pot Zombies (2005) - cannabis
• Prayer of the Rollerboys (1990) - fictional drug "mist"
• The Principles of Lust (2003) - cannabis, cocaine, MDMA, ayahuasca (yage), pills
• The Private Lives of Pippa Lee (2009) - dexedrine, amphetamine
• Project X (2012) - ecstasy, cocaine, cannabis
• Protégé (2007) - heroin
• Prozac Nation (2001) - cannabis, cocaine, prozac (fluoxetine) and ecstasy^[1]
• Psych-Out (1968) - LSD and DOM
• Puddle Cruiser (1996) - cannabis
• Puff, Puff, Pass (2006) - cannabis
• Pulp Fiction (1994) - cocaine, heroin, cannabis^[8]
• Punisher War Zone (2008) - cocaine, methamphetamine
• Pure (2002) - heroin

Q

• Quadrophenia (1979) - amphetamines (known as "Blues" in the film)
• Quiet Cool (1986) - marijuana

R

• Rachel Getting Married (2008) - cannabis, Oxycodone (Percocet)
• Rave - The Ultimate Party (2000) - MDMA
• Ray (2004) - heroin, cannabis
• Rebound: The Legend of Earl "The Goat" Manigault (1996) - heroin
• Red Angel, aka Akai tenshi (1966) - morphine
• Reefer Madness (1936) - cannabis^[8]
• Reefer Madness (2005 remake) - cannabis
• Reeker (2005) - MDMA
• Amants réguliers, Les (2005) - cannabis
• Reindeer Spotting – Escape from Santaland (2010) - Subutex, amphetamine, heroin and cannabis
• Remember the Daze (2007) - mushrooms, cannabis
• Reno 911!: Miami (2007) - cocaine
• Rent (2005) - heroin, cannabis
• Repo! The Genetic Opera (2008) - fictional drug "Zydrate," a powerful and highly-addictive painkiller and hallucinogenic, manufactured by GeneCo, for people undergoing surgery; "graverobbers" sell a cheap version of Zydrate on the black market extracted from the blood of the dead
• Repo Man (1984) - cannabis, cocaine and amphetamines
• Requiem for a Dream (2000) - heroin, cannabis, MDMA, cocaine, amphetamines, barbiturates
• Return to Paradise (1998) - cannabis resin
• Revenge of the Nerds (1984) - cannabis
• Riding the Bullet (2004) - cannabis
• Rich Kids (1979) - cocaine
• Righteous Kill (2009) - cocaine
• Riot on Sunset Strip (1967) - marijuana and LSD
• Rise of the Footsoldier (2007) - steroids, cannabis, cocaine, heroin, MDMA, ketamine
• Rise of the Planet of the Apes (2011) - fictional drug "ALZ-113"
• Risky Business (1983) - cannabis
• RoboCop (1987) - cocaine
• RoboCop 2 (1990) - fictional drug "Nuke"
• RocknRolla (2008) - cannabis, cocaine, heroin
• Rockers (1978) - cannabis
• Rolling (2007) - MDMA, cannabis
• Rolling Kansas (2003) - cannabis
• Romeo + Juliet (1996) - a substance that is similar to, or actually is MDMA, known as "Queen Mab"
• The Rose (1979) - heroin, barbiturates
• The Royal Tenenbaums (2001) - cannabis, cocaine, mescaline
• Rube in an Opium Joint (1904) - opium; considered the oldest still existing motion picture to contain substance abuse
• The Rules of Attraction (2002) - mushrooms, cocaine, LSD, methamphetamine, cannabis and MDMA
• The Rum Diary (2011) - LSD
• Run! Bitch Run! (2009) - cannabis, crack/cocaine
• The Runaways (2010) - cocaine, MDMA, Quaaludes
• Running with Scissors (2006) - prescription medications
• Rush (1991) - heroin, tobacco, amphetamines, cannabis, cocaine

S

• The Salton Sea (2002) - methamphetamine
• Sample People (2000) - fictional drug "glow" and cocaine
• Sausage Party (2016) - cannabis, bath salts
• Savage Beach (1989) - heroin
• Savages (2012) - cannabis, cocaine
• Saving Grace (2000) - cannabis
• A Scanner Darkly (2006) - cocaine, cannabis, methamphetamine, and "Substance D," a fictional psychoactive stimulant
• Scarface (1983) - cocaine, heroin, Quaaludes
• Scott Pilgrim Vs. The World (2010) - cannabis, mushrooms
• Scrooged (1988) - marijuana and heroin
• Secrets of Chinatown (1935) - opium
• The Serpent and the Rainbow (1988) - Haitian witch concoction containing scopolamine
• The Seven-Per-Cent Solution (1976) - cocaine
• Sex and the City (2008) - marijuana
• Sex & Drugs & Rock & Roll (2010) - cannabis, amphetamines, cocaine
• Sexy Bitches (2005) - cannabis
• The Sexy Killer (1976) - heroin
• Shank (2010) - khat, cannabis
• She Shoulda Said 'No'! (1949) - cannabis
• Sherrybaby (2004) - heroin
• Shot List (2009) - LSD, cocaine, cannabis
• Shrink (2009) - cannabis, amphetamine, cocaine
• Shrooms (2007) - magic mushrooms, cannabis
• Siberia (1998) - cannabis, MDMA, amyl nitrate
• Sid and Nancy (1986) - heroin, methadone, cannabis^[2]
• The Skeleton Twins (2014) - nitrous oxide, alcohol, cannabis
• Skidoo (1968) - LSD
• Slackers (2002) - cannabis
• SLC Punk! (1999) - LSD, oxycodone, Perocet, cannabis
• Sleepaway Camp II: Unhappy Campers (1988) - marijuana
• Slim Susie (2003) - amphetamine, heroin, cannabis
• Smiley Face (2007) - cannabis
• Smoked. The Movie (2012) - cannabis, cocaine^[16]
• Smokin' Aces (2007) - cocaine
• The Social Network (2010) - cocaine, cannabis
• Something Weird (1967) - LSD
• Sorted (2000) - heroin, MDMA, methamphetamine, pills
• Soul Plane (2004) - mushrooms, cannabis
• Southwest Nine (2004) - LSD, MDMA, cannabis
• Spring Break (1983) - marijuana
• Spring Breakers (2013) - marijuana, crack/cocaine
• Spun (2002) - methamphetamine^[8]
• Square Grouper: The Godfathers of Ganja (2011) - cannabis
• Squeeze (1997)
• Stark Raving Mad (2002) - cannabis, GHB, MDMA
• Starsky & Hutch (2004) - cocaine
• State Property (2002) - cannabis, crack/cocaine
• Steal This Movie (2000) - cannabis
• Steppenwolf (1974)
• Steve-O: Demise And Rise - cannabis, LSD, PCP, cocaine, nitrous oxide, pills
• Stoned (2005) - cannabis, hashish, LSD, DMT, psilocybin, cocaine, alcohol, amphetamines, barbiturates^[8]
• The Stoned Age (1994) - cannabis
• Stoned: In The Beginning (2010) - cannabis, LSD, cocaine, sleeping pills, crack
• Strange Days (1995) - fictional drug "SQUID"
• Strange Wilderness (2008) - cannabis, nitrous oxide
• Streets of Blood (2009) - cocaine/crack
• Stripes (1981) - LSD ^[17]
• Stuck in Love" (2012)- cannabis, cocaine
• The Student Nurses (1970) - LSD^[18]
• The Substance: Albert Hofmann's LSD (2011) - LSD
• Sugarhouse (2007) - cannabis, crack/cocaine
• Summer of Sam (1999) - cocaine, cannabis
• Sunset Strip (2000) - cannabis, cocaine, LSD, alcohol
• Super Fly (1972) - cocaine, cannabis
• Super High Me (2007) - cannabis
• Super Troopers (2001) - cannabis, psychedelic mushrooms, LSD
• Superbad (2007) - cocaine, cannabis
• Surfer, Dude (2008) - cannabis
• S.W.A.T.: Firefight (2011) - cannabis
• Sweet Bird of Youth (1962) - amphetamine, cannabis (resin)
• Sweet Nothing (1996) - crack cocaine
• Synanon (1965) - heroin

T

• Taking Off (1971) - cannabis
• Taking Woodstock (2009) - cannabis, LSD
• Taxi 3 (2003) - cannabis and cocaine
• Ted (2012) - cannabis, psychedelic mushrooms and cocaine implicated
• Ted 2 (2015) - cannabis and cocaine implicated
• Tenacious D in The Pick of Destiny (2006) - cannabis, psychedelic mushrooms
• Terminal Bliss (1992) - marijuana, cocaine, LSD and methamphetamine^[19][20]
• Thank You For Smoking (2006) - cigarettes, nicotine (patches)
• That Was Then... This Is Now (1985) - unknown "colorful" pills (assumed LSD)
• That's Your Funeral (1972) - cannabis
• The Thing (1982) - cannabis
• Thirteen (2003) - inhalants ("Airduster"), LSD, cannabis, cocaine, various prescription drugs, MDMA (in the form of "Booty Juice")^[1]
• This Is England (2006) - cannabis
• This Is the End (2013) - cannabis, MDMA, Magic Mushrooms
• Thriller - A Cruel Picture (1973) - heroin
• Through a Blue Lens (1999) - crack cocaine, heroin
• Thumbsucker (2005) - cannabis, cocaine, and ritalin
• Thursday (1998) - cocaine, cannabis
• Tideland (2005) - heroin
• The Tingler (1959) - first film to feature LSD
• Toad Road (2012) - acid, various other drugs
• Tommy (1975) - heroin, LSD
• Tomorrow, When the War Began (2010) - cannabis
• The Town (2010) - oxycontin, cocaine
• Trading Places (1983) - marijuana
• Traffic (2000) - cannabis, cocaine, heroin, crack cocaine
• Trailer Park Jesus (2012) - LSD^[21]
• Training Day (2001) - cannabis, crack cocaine, and PCP
• Trainspotting (1996) - heroin, opium, MDMA, amphetamines, Valium, hashish, morphine, diamorphine, cyclizine, codeine, temazepam, nitrazepam, phenobarbitone, sodium amytal, dextropropoxyphene, methadone, nalbuphine, pethidine, pentazocine, buprenorphine, dextromoramide, chlormethiazole^[2]
• Transformers: Revenge of the Fallen (2009) - cannabis brownies
• Trapped in a Purple Haze (2000) - heroin
• Trash (1970) - heroin
• The Trip (1967) - LSD, cannabis^[1]
• The Tripper (2007) - cocaine, nitrous oxide, cannabis, LSD, MDMA
• True Romance (1993) - cocaine, cannabis
• Tweek City (1995) - methamphetamine
• Twelve (2010) - cannabis, Twelve (fictional drug with similar effects to MDMA and cocaine), many drugs referred to
• Twin Peaks: Fire Walk With Me (1992) - cocaine
• Twin Town (1997) - cannabis, heroin, cocaine, magic mushrooms, glue

U

• Uncivilised (1937) - opium
• The Union: The Business Behind Getting High (2007) - cannabis
• Up in Smoke (1978) - cannabis, LSD, pills, amphetamines
• The Usual Suspects (1995) - cocaine
• Udta Punjab (2016) - cocaine, heroin

V

• Valley of the Dolls (1967) - barbiturates (Seconal, Nembutal, Amytal), amphetamines (Dexedrine), and Demerol
• Veronika Voss (1982) - opiates
• Very Bad Things (1998) - marijuana and cocaine
• A Very Brady Sequel (1996) - magic mushrooms

W

• The Wackness (2008) - cannabis, cocaine, methylphenidate and anti-depressants
• Waiting... (2005) - cannabis and inhalants
• Walk Hard: The Dewey Cox Story (2007) - cannabis, cocaine, Quaaludes, PCP, amphetamine, pills ("uppers and downers"), LSD and Viagra
• Walk the Line (2005) - cocaine and amphetamine
• The Warriors - marijuana
• The Wash (2001) - cannabis
• Weekend at Bernie's (1989) - cocaine and fictional lethal injection drug
• Weirdsville (2007) - heroin, cannabis
• We're the Millers (2013) - cannabis
• What Just Happened (2008) - hydromorphone, benzodiazepines, cocaine is referred to
• Where the Boys Are '84 (1984) - marijuana
• Where the Buffalo Roam (1980) - cannabis, cocaine and mescaline
• Where the Day Takes You (1992) - multiple drugs
• While We're Young (2015) - ayahuasca
• Who'll Stop the Rain (1978) - heroin
• Why Do Fools Fall in Love (1998)^[1]
• The Wild Angels (1966) - marijuana and heroin
• Wild in the Streets (1968) - LSD^[2]
• Winter's Bone (2010) - methamphetamine, cocaine, marijuana
• Withnail and I (1987) - cannabis, speed and other pills
• Without a Paddle (2004) - cannabis
• The Wolf of Wall Street (2013) - cocaine, crack cocaine, Quaaludes, and a mention of cannabis, Xanax and morphine
• Woodstock (1970) - cannabis, LSD, and other psychedelics
• Wonderland (2003) - cannabis, methamphetamine, cocaine, heroin, Quaaludes

Y

• Y Tu Mamá También (2001) - marijuana
• Yellow Submarine (1968)^[2] - largely considered to be like an LSD trip
• The Young Nurses (1973) - cocaine
• Your Highness (2011) - an unnamed herb that cause hallucinations
• Youth In Revolt (2009) - marijuana, mushrooms

Z

• Zapped! (1982) - marijuana
• Zombieland (2009) - marijuana