This is a list of notable alumni of DePaul University in Chicago.
Musicians
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- Jeremy Barnes, drummer of indie rock bands Neutral Milk Hotel, Bright Eyes
- Frank Catalano, jazz musician
- Ryan Cohan, jazz musician
- Oto Carrillo, horn player in the Chicago Symphony Orchestra
- Brian Culbertson, jazz musician
- Greg Davis, musician, sound artist
- Tristen Gaspadarek, singer-songwriter
- James William Guercio, producer for the band Chicago and former owner of Country Music Television
- Matt Henkels, guitarist for the band Beach Bunny
- Terry Kath, guitarist and vocals for the band Chicago
- Lorin Levee, principal clarinet for the Los Angeles Philharmonic
- Ramsey Lewis, jazz musician
- Lee Loughnane, trumpet player for the band Chicago
- Abraham Lubin, Hazzan
- Ray Manzarek, keyboardist for 1960s rock band The Doors
- Kris Myers, drummer of the Chicago-based progressive rock group Umphrey's McGee
- Tim Nordwind, bass and vocals for the band Ok Go
- Jim O'Rourke, Grammy Award-winning producer, composer, musician, sound-artist
- James Pankow, trombone player for the band Chicago
- Walter Parazaider, woodwind player for the band Chicago
- George Perle, Pulitzer Prize-winning composer
- Christian Picciolini, guitarist for Random55; CEO of Goldmill Group; former CEO of Sinister Muse Records and Chaos Records
- Matana Roberts, Saxophonist and Composer
- Lili Trifilio, guitarist and vocalist for the band Beach Bunny[5]