Lew is the surname of:

• Barzillai Lew (1743–1822), African American soldier and musician
• Cameron Lew (born 1995), American musician and sole studio member of music project Ginger Root
• Connor Lew (born 2005), American football player
• Emma Lew (born 1962), Australian poet
• Harry Lew (1884–1963), American basketball player
• Lew Hing (1858–1934), Chinese-born American industrialist
• Jack Lew (born 1955), United States Secretary of the Treasury
• James Lew (born 1952), American martial arts actor
• Michael Lew (born 1965), Dutch scientist
• Peter Lew (born 1970), Australian businessman, son of Solomon Lew
• Randy Lew (born 1985), American professional poker player
• Ronald S. W. Lew (1941–2023), United States District Court judge
• Shoshana Lew, (born 1983), American career government administrator
• Solomon Lew (born 1945), Australian businessman
• Lew Syn Pau, Singaporean politician
• Walter K. Lew, Korean-American poet and scholar
• Lew Yih Wey (born 1991), Malaysian swimmer