Protein-coding gene in the species Homo sapiens
IFIT2 |
---|
|
|
Identifiers |
---|
Aliases | IFIT2, G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42, interferon induced protein with tetratricopeptide repeats 2, ISG-54 |
---|
External IDs | OMIM: 147040 MGI: 99449 HomoloGene: 1187 GeneCards: IFIT2 |
---|
|
|
|
|
|
Wikidata |
|
Interferon-induced protein with tetratricopeptide repeats 2 or IFIT2 is a protein found in humans which is encoded by the IFIT2 gene.[5][6][7]
Clinical significance
IFIT2 may play a role in prevention of tumor progression.[8] Indeed, IFIT2 gene has been detected progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from uterine cervical preneoplastic lesions at different levels of malignancy.[9] For this reason, this gene is likely to be associated with tumorigenesis and may be a potential prognostic marker for uterine cervical preneoplastic lesions progression.[9]