Help Me may refer to:

• Mayday (distress signal), the English pronunciation of the French phrase "venez m'aider" ("Come help me")
• "Help Me" (House), the sixth-season finale of House

Songs

• "Help Me" (Sonny Boy Williamson II song), a 1963 blues standard first recorded by Sonny Boy Williamson II
• "Help Me" (Johnny Northern, Ralph Bailey song), a Northern Soul song written by Johnny Northern and Ralph Bailey
• "Help Me" (Larry Gatlin song), a song covered by Kris Kristofferson in 1972 and Elvis Presley in 1974
• "Help Me" (Joni Mitchell song), a 1974 song from the album Court and Spark
• "Help Me" (Nick Carter song), a 2002 single from the album Now or Never
• "Help Me" (Alkaline Trio song), a 2008 single from the album Agony and Irony
• "Help Me" (Tinchy Stryder song), a 2012 single from the album Full Tank
• "Help Me", a song by Chris Brown from his 2007 album Exclusive
• "Help Me", a song by Demi Lovato featuring Dead Sara from the album Holy Fvck
• "Help Me", a song by Deuce from the album Nine Lives
• "Help Me", a song by E-40 from his 2012 album The Block Brochure: Welcome to the Soil 1
• "Help Me!" (Marcy Levy and Robin Gibb song), a 1980 song from Times Square: The Original Motion Picture Soundtrack
• "Help Me!!" (Morning Musume song), a 2013 single
• “Help me”, a song by Johnny Cash
• “Help me”, a song by Joni Mitchell
• “Help me”, a song by Tom Petty & The Heartbreakers