Names | |
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IUPAC name
Methyl glycinate hydrochloride
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Systematic IUPAC name
Methyl 2-aminoacetate hydrochloride | |
Identifiers | |
3D model (JSmol)
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ECHA InfoCard | 100.024.672 |
EC Number |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C3H8ClNO2 | |
Molar mass | 125.55 g·mol−1 |
Appearance | white solid |
Melting point | 175–176 °C (347–349 °F; 448–449 K) |
Hazards | |
GHS labelling:[1] | |
Warning | |
H315, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Glycine methyl ester hydrochloride is the organic compound with the formula [CH3O2CCH2NH3]Cl. A white, water-soluble solid, it is the hydrochloride of the methyl ester of the amino acid glycine.
Glycine methyl ester hydrochloride can be prepared by treatment of glycine with 2 equivalents of trimethylsilyl chloride, followed by the addition of methanol.[2][3]
Upon treatment with base, the salt converts to glycine methyl ester.[4]
Glycine methyl ester (and other esters of glycine) are not shelf-stable, tending to polymerize when stored at room temperature[4] or convert to diketopiperazine. The hydrochloride is shelf-stable.