Protein-coding gene in the species Homo sapiens
GTF2H4 Identifiers Aliases GTF2H4 , general transcription factor IIH, polypeptide 4, 52kDa, P52, TFB2, TFIIH, general transcription factor IIH subunit 4External IDs OMIM : 601760 ; MGI : 1338799 ; HomoloGene : 7090 ; GeneCards : GTF2H4 ; OMA :GTF2H4 - orthologs Gene ontology Molecular function Cellular component Biological process
termination of RNA polymerase I transcription
regulation of transcription, DNA-templated
phosphorylation of RNA polymerase II C-terminal domain
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
transcription by RNA polymerase II
transcription, DNA-templated
cellular response to DNA damage stimulus
global genome nucleotide-excision repair
transcription-coupled nucleotide-excision repair
transcription initiation from RNA polymerase II promoter
nucleotide-excision repair, DNA incision
DNA repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 5'-to lesion
DNA duplex unwinding
positive regulation of ATP-dependent activity
nucleotide-excision repair, DNA duplex unwinding
nucleotide-excision repair, DNA incision, 3'-to lesion
transcription elongation from RNA polymerase I promoter
Sources:Amigo / QuickGO
Wikidata
General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene .[5] [6]
Interactions
GTF2H4 has been shown to interact with:
Transcription factors and intracellular receptors
(1) Basic domains
(1.1) Basic leucine zipper (bZIP )(1.2) Basic helix-loop-helix (bHLH )
Group A Group B Group C bHLH-PAS Group D Group E Group F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors