Protein-coding gene in the species Homo sapiens
Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (GPI-HBP1) also known as high density lipoprotein-binding protein 1 is a protein that in humans is encoded by the GPIHBP1 gene .[5]
Function
Dietary fats are packaged by intestine into triglyceride -rich lipoproteins called chylomicrons . The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LPL) along the luminal surface of capillaries, mainly in heart, skeletal muscle, and adipose tissue. GPIHBP1 is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons.[5] [6]
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .