Names | |
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Preferred IUPAC name
2′-Hydroxy-4,4′,6′-trimethoxychalcone | |
Other names
Flavokawain A
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Identifiers | |
3D model (JSmol)
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2224776 | |
PubChem CID
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UNII | |
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Properties | |
C18H18O5 | |
Molar mass | 314.337 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Flavokavain A is a flavokavain found in the kava plant.[1] It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.[2]
Flavokavains A and B enhance hepatotoxicity of paracetamol, underscoring a potentially serious interaction between paracetamol and kava.