Citadel Square Baptist Church was the fourth Baptist church built in Charleston, South Carolina. The church began as an outgrowth of the First Baptist Church when, in 1854, a dozen members sought permission to establish a new church for the upper peninsula. The new church was to have been known as the Fourth Baptist Church but, when an existing Baptist church closed, leaving only three Baptist churches, the name was changed to Citadel Square Baptist Church. The name refers to the church's location on upper Meeting St., immediately across from Marion Square (which at the time was the location of the Citadel).

Construction of the church at 328 Meeting St. began in June 1855. The new building was opened on November 23, 1856. A Sunday school building added in 1891 was replaced in 1921. In April 1951, an educational building was added to the campus.^[1]