Dr. Algernon C. Edwards, a surgeon in the Cinemax television series The Knick
Algernon, the name of Detective Jake Peralta's desk mouse in Brooklyn Nine-Nine
A fictional character in Archer is called Doctor Algernon Krieger. (Krieger's actual name is Algernop, but this is likely a change to get through customs)
Aljernon Half-Dream, a character in the video game Shadowrun Returns and its sequels.[1]
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