AFX may stand for:
- AFX Windows Rootkit 2003, a user-mode Windows rootkit that hides files, processes and registry
- AFX News Limited, a London financial news agency
- Animation Framework eXtension, a model for representing 3D graphics content defined in MPEG-4 Part 16
- Aphex Twin (born 1971), electronic musician
- Application Framework eXtensions, an old name for the Microsoft Foundation Class Library (MFC)
- Aurora AFX, a brand of slot car marketed by Aurora Plastics Corporation
- A replacement for the A-6 Intruder, developed by the United States Navy and United States Air Force (canceled in 1991)
This disambiguation page lists articles associated with the title AFX.
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