Names | |
---|---|
Preferred IUPAC name
(6S)-6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol | |
Identifiers | |
3D model (JSmol)
|
|
Abbreviations | 5-OH-DPAT |
ChEMBL | |
ChemSpider | |
MeSH | 5-Hydroxy-2-N,N-dipropylaminotetralin |
PubChem CID
|
|
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C16H25NO | |
Molar mass | 247.382 g·mol−1 |
log P | 3.55 |
Acidity (pKa) | 10.543 |
Basicity (pKb) | 3.454 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
5-OH-DPAT is a synthetic compound that acts as a dopamine receptor agonist with selectivity for the D2 receptor and D3 receptor subtypes.[1][2] Only the (S)-enantiomer is active as an agonist, with the (R)-enantiomer being a weak antagonist at D2 receptors.[3] Radiolabelled 11C-5-OH-DPAT is used as an agonist radioligand for mapping the distribution and function of D2 and D3 receptors in the brain,[4][5] and the drug is also being studied in the treatment of Parkinson's disease.[6][needs update]