Monoclonal antibody | |
---|---|
Type | Single-chain variable fragment |
Source | Humanized |
Target | IL6R |
Clinical data | |
Other names | ALX0061 |
ATC code |
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Identifiers | |
CAS Number | |
ChemSpider |
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UNII | |
KEGG | |
Chemical and physical data | |
Formula | C1118H1757N315O364S8 |
Molar mass | 25691.68 g·mol−1 |
Vobarilizumab (INN; development code ALX0061) is a humanized bispecific nanobody (Llama-derived heavy-chain only (Vhh) antibody) designed for the treatment of inflammatory autoimmune diseases.[1][2][3]
This drug was developed by Ablynx NV to block interleukin-6 receptor. Vobarilizumab has been evaluated in patients with rheumatoid arthritis[4] as well as in lupus.[5]