Jack Clifford may refer to:

• Jack Clifford (actor) (1888–1974), also known as Jack "Rube" Clifford, American actor of film and stage
• Jack Clifford (1880–1956), born Virgil James Montani, Italian-born American boxer and ragtime dancer, former husband of Evelyn Nesbit
• Jack Clifford (rugby union) (born 1993), Australian-born rugby union player who played for England
• John Cliff (actor) (1918–2001), born as Jack Clifford, American actor of film and television

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