The Grand Opera House (Initially Wade's Opera House) was an opera house in San Francisco, which opened in 1874, and which was destroyed in the 1906 San Francisco earthquake.

• "War Memorial Opera House" (PDF). verplanck consulting. Archived from the original (PDF) on 2016-04-13. ...the Wade (later Grand) Opera House. Located on the north side of Mission Street, just west of Third Street, the Grand Opera House perished in 1906, along with most of the city's other opera houses, including the Tivoli Opera House and the Orpheum Theater.

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37°47′09″N 122°24′11″W / 37.78593°N 122.40299°W / 37.78593; -122.40299