Edward Wilson may refer to:

• Ed Wilson (artist) (1925–1996), African American sculptor
• Ed Wilson (baseball) (1875–?), American baseball player
• Ed Wilson (singer) (1945–2010), Brazilian singer-songwriter
• Ed Wilson, American television executive
• Ed Wilson, Australian jazz musician, co-leader of Daly-Wilson Big Band
• Edward Wilson, clergyman and the founder of Wilson's School, originally in Camberwell, London
• E. O. Wilson (born Edward Osborne Wilson, 1929–2021), American entomologist and biologist
• Edward "Tug" Wilson (1921–2009), founder and first commander of the Abu Dhabi Defence Force
• Edward Adrian Wilson (1872–1912), English Antarctic explorer
• Edward E. Wilson (1867–1952), African American lawyer
• Edward Junior Wilson (born 1984), Liberian footballer
• Edward L. Wilson (born 1931), American civil engineer
• Edward Livingston Wilson (1838–1903), American photographer, writer and publisher
• Edward Wilson (MP) (1719–1764), English MP for Westmorland
• Edward Wilson (actor) (1947–2008), English actor and theatre director
• Edward Wilson (engineer) (1820–1877), railway engineer in England
• Edward Wilson (journalist) (1813–1878), 19th-century Australian journalist
• Edward Wilson (novelist), 21st century British writer of spy novels
• Edward Francis Wilson (1844–1915), Canadian Anglican missionary and clergyman
• Edward Pellew Wilson Jr. (1832–1899), British-Brazilian businessman
• Tay Wilson (Tennant Edward Wilson, 1925–2014), member of the International Olympic Committee from New Zealand
• Edward H. C. Wilson (1820–1870), Justice of the Michigan Supreme Court

Fictional character

• Edward Wilson, the character played by Matt Damon in The Good Shepherd