Carl L. Faingold is an American neuroscientist who is a professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois; he is a founding faculty member of both the department and the School of Medicine. He has had an extensive career as a medical and graduate student educator as well as a researcher in brain mechanisms. He is a specialist in the actions of drugs on brain activity at the level of the single neuron as it relates to networks of neurons in awake behaving animals.[citation needed]
Faingold received a B.S. in pharmacy from the University of Illinois at Chicago in 1965, and a Ph.D. in pharmacology from Northwestern University in 1970. This was followed by a postdoctoral fellowship at the University of Missouri Institute of Psychiatry.
A major research direction in Faingold's lab is in the area of sudden unexpected death in epilepsy (SUDEP), which is a devastating and relatively rare problem that can occur in patients with epilepsy.[1] Since first publishing about a mouse model of SUDEP in 2006 in DBA mice,[2] his lab has explored the role of brain chemicals, serotonin and adenosine, in potential preventative treatments for SUDEP in these mice,[2] including a possible role of agents that enhance the action of serotonin in SUDEP prevention.These agents include selective serotonin reuptake inhibitors (SSRIs) which prevent SUDEP in mice with some evidence of potential usefulness in human epileptic patients as well.[3]
His lab has published several recent papers on the subject of SUDEP prevention in two mouse models of SUDEP in DBA/1 and DBA/2 mice.[4][5]
He has participated in the writing of the "AMSPC Knowledge Objectives in Pharmacology" as co-editor with Richard Eisenberg, . of the2012 update and expansion of these pharmacology teaching objectives.[6]He also served as co-editor ofBrody's Human Pharmacologywith Lynn Wecker, George Dunaway, Lynn Crespo and Stephanie Watts.[citation needed]
In 2014, he published a book with co-editor, Hal Blumenfeld, Professor of Neurology, Neuroscience and Neurosurgery at Yale University School of Medicine.Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics[7]